“…These studies involved not only the flows with simple agitators and at low Reynolds numbers (Smith et al, 1990;Lu et al, 1995), but also the flows with complex agitators and at high Reynolds numbers (Derksen et al, 1999;Myers et al, 1999;Bittorf et al, 2000). On the other hand, experimental methods have also been widely adopted to study the flow in the stirred tank (Li et al, 1996;Mao et al, 1998, Schäfer et al, 1998Bittorf et al, 2000Bittorf et al, , 2001 and the results have been used to improve the agitator design and scale-up design in engineering applications.…”