The measure of diversity

Laxton, R. R.

doi:10.1016/0022-5193(78)90302-8

Cited by 114 publications

(44 citation statements)

References 5 publications

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“…Increment of diversity (ID) algorithm was a classifier which has been successfully used in identification of protein folds and complex secondary structures in recent years (Laxton, 1978;Li and Lu, 2001;Hu et al, 2010). In the state space of s dimension, the measure of diversity source X{n 1 , n 2 ,…, n s } was:…”

Section: Increment Of Diversity (Id) Valuementioning

confidence: 99%

Identification of Ca2+-binding residues of a protein from its primary sequence

Jiang

Geriletu

et al. 2016

Genet. Mol. Res.

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ABSTRACT. Calcium is one of the most abundant minerals in the human body, playing a critical role in many cellular activities by interacting with different calcium ion (Ca 2+ )-binding proteins. Therefore, the correct identification of Ca 2+ -binding residues is essential for protein functional research. In this study, a new method was developed to predict Ca 2+ -binding residues from the primary sequence without using three-dimensional information. Through statistical analysis, four kinds of feature parameters were extracted from amino acid sequences: the increment of diversity values of amino acid composition, the matrix scoring values of position conservation, the autocross covariance of physicochemical properties, and the center motif. These features served as input for a support vector machine to predict Ca 2+ -binding residues. This method was tested on four well-established datasets using a five-fold cross-validation. The accuracies and Matthews correlation coefficients were 75.9% and 0.53 (dataset 1), 79.2% and 0.58 (dataset 2), 77.4% and 0.55 (dataset 3), and 79.1% and 0.58 (dataset 4). Comparative results show that the developed method outperforms previous methods. Based on this study, a web server was developed for predicting Ca 2+ -binding

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Section: Increment Of Diversity (Id) Valuementioning

confidence: 99%

Identification of Ca2+-binding residues of a protein from its primary sequence

Jiang

Geriletu

et al. 2016

Genet. Mol. Res.

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show abstract

“…O índice de Brillouin, considerado adequado para medir a diversidade e o mais aj ustado quando os dados representam uma coleção (MARGALEF 1958;PIELOU 1966PIELOU , 1975LAXTON 1978;MAGURRAN 1988), indicou Ponta Grossa como o local de maior diversidade de Saturniidae e Fênix, o de menor. Situação idêntica foi definida pelo índice de Shannon.…”

Section: íNdices De Diversidade Dominância E Uniformidade íNdices Deunclassified

Levantamento da fauna entomológica no estado do Paraná III: Saturniidae (Lepidoptera)

1997

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“…@ "6. According to the concept of diversity and measure of diversity (Laxton, 1978), we may de-"ne the measure of diversity. …”

Section: Theoretical Methodsmentioning

confidence: 99%

“…Rules for recognition of the structural class of a protein from its secondary structural elements, especially from the regular structural elements, have been proposed (Luo & Li, 2000). In this article, according to the number of -helices, -strands, and fragments within a protein secondary structure sequence, we shall utilize the measure of diversity and increment of diversity (Laxton, 1978) in information theory of biology to predicate the structural classes of the protein. The sole prediction parameter*the increment of diversity is used as the index of prediction of structural class of a protein by our algorithm.…”

Section: Introductionmentioning

confidence: 99%

The Prediction of the Structural Class of Protein: Application of the Measure of Diversity

Zhi-qing

2001

Journal of Theoretical Biology

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The measure of diversity

Cited by 114 publications

References 5 publications

Identification of Ca2+-binding residues of a protein from its primary sequence

Identification of Ca2+-binding residues of a protein from its primary sequence

Levantamento da fauna entomológica no estado do Paraná III: Saturniidae (Lepidoptera)

The Prediction of the Structural Class of Protein: Application of the Measure of Diversity

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