The Measurement of Left Ventricular Function and the Detection of Wall Motion Abnormalities with High Temporal Resolution Ecg-Gated Scintigraphic Angiocardiography

Assessment of Ventricular Function by Radionuclide Angiography: Applications and Results

“…To follow the movement of blood into and out of the cardiac chambers during the cardiac cycle, images of finite du ration are obtained rapidly and sequentially during the cardiac cycle. The temporal dura tion of each image and, thus, the number of images obtained per cardiac cycle is directly determined by settings on a computer, which can digitize and store the quantitative infor mation regarding the number of gamma photons incident on the detector at any one location at any given time [1, [43][44][45][46], This digitized information can be displayed graph ically by the computer. Rapid sequential dis play of all images is.…”

“…In or der to maximize the information content available for analysis of each point on the time-volume curve, the computer can super impose the corresponding images from suc cessive cardiac cycles, determining the ap propriate points of superimposition by refer ence to a gating signal, usually supplied by an electrocardiographic impulse [47], Two approaches to radionuclide cinean giography are available. Either a single bolus of isotope can be followed in its passage through the heart ('first pass method') [3,12,48,49] or the isotope can be allowed to equil- ibrate within the intravascular compartment prior to imaging ('equilibrium method') [1, [43][44][45][46]. Much controversy has been engen dered during the past 7 years regarding the relative merits of the two approaches.…”