The mechanism of chitosan degradation by gamma and e-beam irradiation

Gryczka, Urszula; Dondi, Daniele; Chmielewski, A.G.; Migdal, W.; Buttafava, A.; Faucitano, A.

doi:10.1016/j.radphyschem.2009.03.081

Cited by 67 publications

(36 citation statements)

References 19 publications

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“…Similar type effect of gamma radiation on molecular weight of chitosan was found by Gryczka et al [15] where gel permeable chromatography (GPC) method was applied for determining molecular weight. Detection of double peaks in bimodal distribution curve of GPC of non-irradiated chitosan depicted that some degradation already occurred during chitosan processing (deacetylation) [15].…”

Section: Effect Of Gamma Radiation On the Molecular Weight Of Extractsupporting

confidence: 74%

“…Deconvolution of the EPR spectra suggested the production of some intermediate radicals during irradiation which helped reveal the mechanism of radiolysis assessed with respect to free radicals. Nitroxyl radicals were identifi ed with EPR spectra while sample was irradiated in the presence of oxygen which provided the evidence of the involvement of amino group in radiolysis mechanism [15]. Our results clearly showed that radiation induced degradation rate of chitosan in dry condition is much lower than that in wet condition.…”

Section: Effect Of Gamma Radiation On the Molecular Weight Of Extractmentioning

confidence: 55%

“…Detection of double peaks in bimodal distribution curve of GPC of non-irradiated chitosan depicted that some degradation already occurred during chitosan processing (deacetylation) [15].…”

Section: Effect Of Gamma Radiation On the Molecular Weight Of Extractmentioning

confidence: 99%

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Application of gamma radiation and physicochemical treatment to improve the bioactive properties of chitosan extracted from shrimp shell

et al. 2017

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The aim of this study is to exploit a suitable chitosan extraction method from the chitin of indigenous shrimp shells by employing different physicochemical treatments and to improve different bioactive properties of this extracted chitosan (CS) by applying gamma radiation. Chitin was prepared from shrimp shell by pretreatment (deproteination, demineralization and oxidation). Chitosan was extracted from chitin by eight different methods varying different physicochemical parameters (reagent concentration, temperature and time) and assessed with respect to the degree of deacetylation, requirement of time and reagents. The method where chitin was repeatedly treated with 121°C for 30 min with 20 M NaOH, produced the highest degree of deacetylation (DD) value (92%) as measured by potentiometric titration, with the least consumption of time and chemicals, and thus, selected as the best suitable extraction method. For further quality improvement, chitosan with highest DD value was irradiated with different doses (i.e., 5, 10, 15, 20 and 50 kGy) of gamma radiation from cobalt-60 gamma irradiator. As the radiation dose was increased, the molecular weight of the wet irradiated chitosan, as measured by the viscosimetric method, decreased from 1.16 × 105 to 1.786 × 103, 1.518 × 103, 1.134 × 103, 1.046 × 103 and 8.23 × 102 dalton, respectively. The radiation treatment of chitosan samples increased the antimicrobial activity significantly in concentration dependent manner on both gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria, as determined by the well-diffusion method. Four to five percent wet chitosan treated with a radiation dose range of 5.0–10.0 kGy rendered the highest antimicrobial activity with least energy and time consumption. Solubility, water binding capacity (WBC) and fat binding capacity (FBC) also improved due to irradiation of chitosan.

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Section: Effect Of Gamma Radiation On the Molecular Weight Of Extractsupporting

confidence: 74%

Section: Effect Of Gamma Radiation On the Molecular Weight Of Extractmentioning

confidence: 55%

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Application of gamma radiation and physicochemical treatment to improve the bioactive properties of chitosan extracted from shrimp shell

et al. 2017

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“…The second stage, is the severe weight loss that is called main region of decomposition in Table 1. It is due to the decomposition of the major components of the composites, mainly the thermal destruction of the pyranose ring and the rupture of the b-glycosidic-linkages between the glycosamine and Nacetylglucoamine moieties 15,16 . So, the thermal decomposition of the composite starts with the breaking of the bond C-O-C and the formation of acetamide C 2 H 5 NO 17 .…”

Section: Resultsmentioning

confidence: 99%

The effect of radiation on the thermal properties of chitosan/mimosa tenuiflora and chitosan/mimosa tenuiflora/multiwalled carbon nanotubes (MWCNT) composites for bone tissue engineering

Martel-Estrada

Santos-Rodríguez

Olivas–Armendáriz

et al. 2014

AIP Conference Proceedings

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The purpose of this study is to examine the effect of gamma radiation and UV radiation on the microstructure, chemical structure and thermal stability of Chitosan/Mimosa Tenuiflora and Chitosan/Mimosa Tenuiflora/MWCNT composites scaffolds produced by thermally induced phase separation. The composites were irradiated and observed to undergo radiation-induced degradation through chain scission. Morphology, thermal properties and effects on chemical and semi-crystalline structures were obtained by scanning electronic microscopy (SEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), FT-IR analysis and X-ray Diffraction. A relationship between radiation type and the thermal stability of the composites, were also established. This relationship allows a more accurate and precise control of the life span of Chitosan/Mimosa Tenuiflora and Chitosan/Mimosa Tenuiflora/MWCNT composites through the use of radiation in materials for use in tissue engineering.

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“…Usually, physical degradation, chemical degradation, and bio-degradation were often employed to improve the solubility of CS (Cai et al, 2011;Gryczka et al, 2009;Patwardhana, Satrio, Brown, & Shanks, 2009;Wasikiewicz & Yeates, 2013;Zawadzki & Kaczmarek, 2010). Among them, chemical degradation is considered to be an ideal method for the preparation of oligo-CS (Sun, Zhou, Xie, & Mao, 2007) because of simple and convenient advantages.…”

Section: Synthesis Of Recombinant Polysaccharidementioning

confidence: 99%

Synthesis, anti-oxidant activity, and biodegradability of a novel recombinant polysaccharide derived from chitosan and lactose

Guo¹,

Ma²,

Wang³

et al. 2015

Carbohydrate Polymers

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The mechanism of chitosan degradation by gamma and e-beam irradiation

Cited by 67 publications

References 19 publications

Application of gamma radiation and physicochemical treatment to improve the bioactive properties of chitosan extracted from shrimp shell

Application of gamma radiation and physicochemical treatment to improve the bioactive properties of chitosan extracted from shrimp shell

The effect of radiation on the thermal properties of chitosan/mimosa tenuiflora and chitosan/mimosa tenuiflora/multiwalled carbon nanotubes (MWCNT) composites for bone tissue engineering

Synthesis, anti-oxidant activity, and biodegradability of a novel recombinant polysaccharide derived from chitosan and lactose

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