The Mechanism of Glucocorticoid Action on the Phytohemagglutinin-Stimulated Lymphocyte

Antineoplastic and Immunosuppressive Drugs1 I

“…Binding of cortisone and hydrocortisone to human, rat and rabbit lymphocytes has been studied and it has been suggested that this binding may be crucial for the steroid inhibition of antigenically-stimulated cells, since the magnitude of the specific binding was proportional to the glucocorticoid activity of a particular hormone (Eurenius et al, 1969).…”