The Mediating Effect of Depression and Disability in the Relationship Between Schizophreniaand Self-Esteem

Demirkol, Mehmet Emin; Tamam, Lut; Namlı, Zeynep; Uğur, Kerim; Karaytuğ, Mahmut Onur

doi:10.1007/s11126-019-09706-4

Cited by 9 publications

(8 citation statements)

References 34 publications

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“…We therefore hypothesize that study participants may have developed coping strategies to deal with the disorder and to adjust to their health condition and to available resources, which, in turn, may have had a positive impact on life satisfaction. On the other hand and similar to previous studies (6,(42)(43)(44)(45)(46), the majority of our sample demonstrated low self-esteem. In addition, more than 40% of patients indicated to have existing needs in the domains of accommodation, work/occupation, looking after home, and finances, and approximately three quarters expressed a need concerning mental health.…”

Section: Discussionsupporting

confidence: 91%

“…Residual positive and affective symptoms were associated with less life satisfaction and a higher degree of patients' needs, whereas both negative and affective symptoms were negatively associated with self-esteem. The latter finding corroborates that of some previous studies (46,54), however, still other investigations found that self-esteem is especially related to positive symptoms (55). Again, these divergent results may be a reflection of sample selection and still other issues, e.g., cultural aspects, may also be relevant in this context.…”

Section: Discussionsupporting

confidence: 88%

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Premorbid Social Functioning and Affective Symptoms Predict Subjective Outcome Among Outpatients With Schizophrenia

et al. 2020

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Improving the subjective outcome of patients is an important target in the treatment of schizophrenia. Accordingly, the aim of the present study was to examine the association of factors deemed relevant in this context, i.e., premorbid functioning, residual symptoms, and side effects of antipsychotic medication, with subjective outcome. To this end, 70 clinically stable outpatients with schizophrenia were included into a cross-sectional study. Premorbid functioning, psychopathology, and side effects were assessed by using the Premorbid Adjustment Scale, the Positive and Negative Syndrome Scale, and the Udvalg for Kliniske Undersogelser Side Effect Rating Scale, respectively. Subjective outcome was measured in terms of life satisfaction (Life Satisfaction Questionnaire), self-esteem (Index of Self-Esteem), and needs for care (Berliner Bedürfnisinventar). Both premorbid social functioning and affective symptoms predicted life satisfaction, self-esteem, and patients' basic needs, whereas positive and negative symptoms predicted needs in the health, social, and functional domains. Concerning side effects, parkinsonism and akathisia showed a significant negative correlation with self-esteem. These findings highlight the complex nature of subjective outcome in patients suffering from schizophrenia. Evidently, premorbid social functioning plays a prominent role in the experienced subjective outcome during the course of the illness. Furthermore, these preliminary findings underscore that constant efforts are essential to treat residual symptoms of the disorder and to avoid extrapyramidal motor side effects of antipsychotic medication. Longitudinal studies are needed to investigate this latter point in more detail.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 88%

Premorbid Social Functioning and Affective Symptoms Predict Subjective Outcome Among Outpatients With Schizophrenia

et al. 2020

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“…Furthermore, a cross-sectional analysis may lead to bias in evaluating mediation, which is a longitudinal process 63 . In our study, we draw on previous research, the alternative models (association of depression with disability) are tested to overcome this limitation 79 . Finally, we need to emphasize that there is a big difference between northern and southern China.…”

Section: Discussionmentioning

confidence: 99%

“…To test the mediation role of pain, depression and HAP with disability, we first used Pearson product-moment correlation coefficient to preliminarily verified the hypothesis that pain, depression, and HAP are associated with disability. To ensure the accuracy of the results, and also to address the limitations of cross-sectional analysis that may lead to bias in evaluating mediation 63,79 . We ran alternative models to test the hypotheses that pain, depression, and HAP are associated with disability.…”

Section: Control Variablesmentioning

confidence: 99%

Effects of pain and depression on the relationship between household solid fuel use and disability among middle-aged and older adults

Jia

Gao

Zhao

et al. 2022

Sci Rep

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Household air pollution (HAP) is suggested to increases people's risk of disability, but mediating mechanisms between HAP and disability remains under-investigated. The aim of this study was to investigate the underlying mechanisms between household air pollution and disability in middle-aged and older adults (i.e., older than 45 years) using a nationally representative prospective cohort. In total, 3754 middle-aged and older adults were selected from the China Health and Retirement Longitudinal Study. Correlation analysis and logistic regression analysis were employed to estimate the association between HAP, pain, depression and disability. Finally, three significant mediation pathways through which HAP directly impacts disability were found: (1) pain (B = 0.09, 95% CI 0.01, 0.02), accounting for 15.25% of the total effect; (2) depression (B = 0.07, 95% CI 0.004, 0.02), accounting for 11.86% of the total effect; (3) pain and depression (B = 0.04, 95% CI 0.003, 0.01), accounting for 6.78% of the total effect. The total mediating effect was 33.89%. This study clarified that HAP can indirectly affect disability through the respective and serial mediating roles of pain and depression. These findings potentially have important implications for national strategies concerning the widespread use of clean fuels by citizens.

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“…Individuals with schizophrenia who also sufer from depression experience a substantial level of disability [14], which impairs their ability to manage their mental and physical health, leading to a vicious cycle of deteriorating disability [15]. Moreover, it has been discovered that depression plays a partial mediator role in the connection between the severity of schizophrenia and disability [16]. Given the magnitude of negative symptoms, the impairments in functioning and well-being, and the risk of suicidality, schizophrenia patients with depressive symptoms should be monitored closely [17].…”

Section: Introductionmentioning

confidence: 99%

The Indirect Effect of Depression between Nightmares and Well‐Being in Lebanese Patients with Schizophrenia

Mahfoud¹,

Ahdab

Helwe

et al. 2023

Perspectives in Psychiatric Care

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Background. Because nightmares seem to be associated with depression in schizophrenia, detecting them early in therapeutic practice might be critical to ensuring effective avoidance of the development of depressive symptomatology. This helps promote well-being and improve the patient’s quality of life and illness prognosis. Therefore, the aim of this study was to examine the indirect effect of depression between nightmares and well-being in a Lebanese sample of patients with schizophrenia. Method. This monocentric cross-sectional study, conducted in July 2022, enrolled patients with chronic schizophrenia admitted to the Psychiatric Hospital of the Cross. Data were collected from a total of 148 participants through face-to-face interviews. The questionnaire included a nightmares measure, PSYRATS, Calgary depression scale for schizophrenia, PTSD checklist for DSM-5, the digit span subset, and WHO-5Well-Being Index. Results. The presence of nightmares was significantly associated with more depression, whereas higher depression was significantly associated with lower well-being. It is noteworthy that the presence of nightmares was not directly associated with well-being. Conclusion. Nightmares lead indirectly to lower well-being in schizophrenia patients, with depression serving as a mediating factor in this association. This suggests that interventions aiming at improving dream content may also have a beneficial effect in reducing depression in schizophrenia leading therefore to better well-being of the patients.

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The Mediating Effect of Depression and Disability in the Relationship Between Schizophreniaand Self-Esteem

Cited by 9 publications

References 34 publications

Premorbid Social Functioning and Affective Symptoms Predict Subjective Outcome Among Outpatients With Schizophrenia

Premorbid Social Functioning and Affective Symptoms Predict Subjective Outcome Among Outpatients With Schizophrenia

Effects of pain and depression on the relationship between household solid fuel use and disability among middle-aged and older adults

The Indirect Effect of Depression between Nightmares and Well‐Being in Lebanese Patients with Schizophrenia

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