The Mediating Role of Mental Adjustment in the Relationship between Perceived Stress and Depressive Symptoms in Hematological Cancer Patients: A Cross-Sectional Study

Abstract

BackgroundDepression is a particularly common psychological disorder that affects cancer patients. Diagnosed with hematological malignancies constitute a serious unpredictable and uncontrollable medical stress situation and patients are susceptible to suffer from depressive symptoms. The aims of the study were to explore the correlation between perceived stress and depressive symptoms in patients with hematological malignancies, and assess the mediating role of mental adjustment between these variables.MethodsA single center, cross-sectional study was performed by convenience sampling between July 2013 and April 2014 in a hospital of China. The Center for Epidemiologic Studies Depression Scale, Perceived Stress Scale, and Mini-Mental Adjustment Scale, as well as questions about demographic and clinical factors was distributed to 300 hematological cancer patients. Completed questionnaires were received from 227 inpatients.ResultsThe results showed that perceived stress was positively correlated with depressive symptoms. The mental adjustment significantly mediated the relationship between perceived stress and depressive symptoms.ConclusionsAmong hematological cancer patients perceived stress may be a risk factor for depressive symptoms, whereas positive coping style might be protective against depressive symptoms. Results showed that medical managers could support the development of mental adjustment in the patients to alleviate psychological disorders.

Stress and the brain: Perceived stress mediates the impact of the superior frontal gyrus spontaneous activity on depressive symptoms in late adolescence

“…Interestingly, we found that perceived stress served as a mediator in the link between SFG spontaneous activity and depressive symptoms. Behaviorally, the association of perceived stress with depressive symptoms has been well established in previous investigations (Bay & Donders, 2008;Bergdahl & Bergdahl, 2002;Chao, 2014;Chen et al, 2017;Eisenbarth, 2012;Farabaugh et al, 2004;Gao et al, 2009;Ghorbani et al, 2008;Hewitt et al, 1992;Kuiper et al, 1986;Lee et al, 2013;Li et al, 2015;Lorenzo-Blanco & Unger, 2015;Martin et al, 1995;Rosal et al, 1997;Tsai & Chang, 2016;Williams et al, 2017). This association was replicated in the current sample (r = .53, p < .001).…”

“…A wealth of previous studies have suggested that perceived stress plays an essential role in the onset and development of depressive symptoms among different populations (Bay & Donders, 2008;Bergdahl & Bergdahl, 2002;Chao, 2014;Chen, Peng, Ma, & Dong, 2017;Eisenbarth, 2012;Farabaugh et al, 2004;Gao, Chan, & Mao, 2009;Ghorbani, Krauss, Watson, & LeBreton, 2008;Hewitt, Flett, & Mosher, 1992;Kuiper, Olinger, & Lyons, 1986;Lee, Joo, & Choi, 2013;Li, Yang, Zhang, Yao, & Liu, 2015;Lorenzo-Blanco & Unger, 2015;Martin, Kazarian, & Breiter, 1995;Rosal et al, 1997;Tsai & Chang, 2016;Williams, Turner-Henson, Davis, & Soistmann, 2017). For example, a number of crosssectional studies have revealed a positive association of perceived stress with depressive symptoms among healthy individuals (Bergdahl & Bergdahl, 2002;Chen et al, 2017;Eisenbarth, 2012;Gao et al, 2009;Ghorbani et al, 2008;Kuiper et al, 1986;Lee et al, 2013;Williams et al, 2017) and clinical patients (Bay & Donders, 2008;Farabaugh et al, 2004;Hewitt et al, 1992;Li et al, 2015;Martin et al, 1995). Furthermore, several longitudinal studies have shown that perceived stress can predict subsequent depressive symptoms in different populations (Chao, 2014;Lorenzo-Blanco & Unger, 2015;Rosal et al, 1997;Tsai &a...…”

Prevalence and predictors of anxiety and depressive symptoms among patients diagnosed with oral cancer in China: a cross-sectional study

“…According to the results of logistic regression analysis, perceived stress was associated with both anxiety and depressive symptoms. Other researches [6,51]suggested that the perceived stress impacted the depressive and anxiety symptoms of cancer patients through their mental adjustment. It could be explained by the fact that a cancer diagnosis is a stressful event for most individuals, and patients experience mental stress such as worries about prognosis and treatments, disruption of daily functions and survival time [52].…”

Prevalence and Predictors of Anxiety and Depressive Symptoms among Patients Diagnosed with Oral Cancer in China: A cross-sectional study

“…According to the results of logistic regression analysis, perceived stress was associated with both anxiety and depressive symptoms. Other researches [6,46]suggested that the perceived stress impacted the depressive and anxiety symptoms of cancer patients through their mental adjustment. It could be explained by the fact that a cancer diagnosis is a stressful event for most individuals, and patients experience mental stress such as worries about prognosis and treatments, disruption of daily functions and survival time [47].…”