“…Practically all of these metastases are lytic, but more recently a mixed metastatic reaction I _ has been reported in a leper skeleton (Ortner et al, 1991). Prior to our example, only three cases present with increased bone COMPARAT'VE PALAEOPATHOLOGICAL EVIDENCE A search of the palaeopathological literature has shown that several examples of metastatic carcinoma are known from archaeological contexts (Allison et al, 1980;Blondiaux, 1984;Brothwell, 1967;Cassidy, 1977;Dastugue, 1965;Gejvall, 1960;Gladykowska-Rzeczycka, 1991;Gregg et al, 1982;Grmek, 1976;Grupe, 1988;Manchester, 1983;Mpiller and Mpiller-Christensen, 1952;Mpiller-Christensen, 1958;Ortner and Putschar, 1985;Pahl et al, 1984;Satinoff, 1972;Soulie, 1980;Steinbock, 1976;Strouhal, 1989Strouhal, , 1991Strouhal and Vyhanek, 1981;Tkocz and Bierring, 1984;Tyson and Dyer Alcauskas, 1980;Waldron, 1987;Wells, 1964). In some of these cases a firm diagnosis of secondary metastatic carcinoma is not possible due to the similarity of quantity, suggestive of a prostatic focus (Ortner and Putschar, 1985;Suzuki, 1989;Tkocz and Bierring 1984).…”