The Medical Care of Patients with Gastrointestinal Bleeding after Endoscopy

Chan, Francis K.L.; Sung, Joseph J.Y.

doi:10.1016/s1052-5157(18)30286-1

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Risk Factors For Bleeding1

Medical Therapy and Helicobacter Pylori Eradication1

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Cited by 7 publications

(2 citation statements)

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“…16 Similarly, while H. pylori is the causative agent in most cases of peptic ulcer disease, there is little evidence that the prevalence of the organism is higher in patients with bleeding ulcers compared with patients with nonbleeding ulcers. 17 Also, studies 18, 19 of the combined effects of NSAIDs and H. pylori on the rates of bleeding due to peptic ulceration have had mixed results.…”

Section: Risk Factors For Bleedingmentioning

confidence: 99%

Proton-Pump Inhibitors for Acute Peptic Ulcer Bleeding

Erstad¹

2001

Ann Pharmacother

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Section: Risk Factors For Bleedingmentioning

confidence: 99%

Proton-Pump Inhibitors for Acute Peptic Ulcer Bleeding

Erstad¹

2001

Ann Pharmacother

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“…In addition, H. pylori eradication therapy has been shown to be more effective than maintenance histamine receptor antagonist therapy in preventing ulcer recurrence after peptic ulcer haemorrhage 46 . Eradication alone is now advocated as sufficient therapy for H. pylori‐ positive patients with ulcer bleeding 51 …”

Section: Medical Therapy and Helicobacter Pylori Eradicationmentioning

confidence: 99%

Bleeding peptic ulcer: An evolving role for surgical intervention

Branicki

Ting

Gertsch

et al. 1998

J of Gastro and Hepatol

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Early surgical intervention was previously advocated in patients > 60 years with bleeding peptic ulcer presenting with haemodynamic instability or ongoing transfusion requirements. It is, however, well recognized that emergency surgical intervention with its inherent risks must be reserved for highly selected patients in whom endoscopy initially fails to control exsanquinating haemorrhage or in whom life‐threatening bleeding recurs. Therapeutic endoscopy for bleeding ulcer has led to a remarkable decline in rebleeding rates, the need for emergency surgery and mortality. Octogenarians are at risk, particularly when ulcer size exceeds 2 cm. Poor surgical candidates make up two‐thirds of patients with major ulcer bleeding and operation is to be avoided if at all possible. Medical therapy with proton pump inhibitor and subsequent eradication of Helicobacter pylori following endoscopic treatment has been shown to be beneficial to outcomes. Should surgery be deemed necessary, it is likely that laparoscopic techniques to control bleeding, with or without the addition of an acid‐reducing procedure, will find a role in haemodynamically stable patients undergoing operation on an early elective basis.

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Consideraciones prácticas para el diagnóstico de la infección por Helicobacter pylori

Argila

Boixeda

2001

Medicina Clínica

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The Medical Care of Patients with Gastrointestinal Bleeding after Endoscopy

Cited by 7 publications

References 87 publications

Proton-Pump Inhibitors for Acute Peptic Ulcer Bleeding

Proton-Pump Inhibitors for Acute Peptic Ulcer Bleeding

Bleeding peptic ulcer: An evolving role for surgical intervention

Consideraciones prácticas para el diagnóstico de la infección por Helicobacter pylori

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