The Menopause Transition and Women’s Health at Midlife: A Progress Report From the Study of Women’s Health Across the Nation (SWAN)

Khoudary, Samar R. El; Greendale, Gail A.; Crawford, Sybil L.; Avis, Nancy E.; Brooks, Maria M.; Thurston, Rebecca C.; Karvonen‐Gutierrez, Carrie; Waetjen, L. Elaine; Matthews, Karen A.

doi:10.1097/01.ogx.0000655420.43344.88

Cited by 63 publications

(109 citation statements)

References 109 publications

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“…The mean age of menopause is 51 years [ 3 ], and in Iran it is 48 years [ 4 ]. Given their increased life expectancy, women are currently spending around a third of their lives in postmenopause, potentially affecting their health and quality of life [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A study on women’s health information needs in menopausal age

et al. 2021

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Menopause is a natural event experienced by women in middle age. To help women manage this event, it is important to identify their health information needs. A study specific questionnaire was used to identify menopausal women’s health information needs and the resources and challenges related to finding information about menopause. A total of 301 women aged 48–55 years completed the questionnaire. Data were analysed using negative binomial regression and chi-square tests. The most frequently sought information was that related to breast cancer (n = 209, 69.5%), hot flushes (n = 200, 66.5%), cervical cancer (n = 194, 64.5%), non-hormonal therapies for menopausal symptoms (n = 192, 64%), laboratory tests (n = 189, 63%) and joint and muscle pain (n = 188, 62.5%). The main sources of information were audiovisual media (n = 171, 57%), obstetricians (n = 165, 55%), friends (n = 157, 52%), family (n = 157, 52%) and the internet (n = 153, 51%). The two main challenges were not knowing how to correctly access information (n = 115, 38%) and not being aware of reliable sources of information (n = 108, 36%). Therefore, it is essential for policymakers and decision-makers to provide reliable and accurate information to increase awareness and reduce anxiety of women experiencing menopause.

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Section: Introductionmentioning

confidence: 99%

A study on women’s health information needs in menopausal age

et al. 2021

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“…Studies of sleep quality during the menopausal transition and post-menopause revealed that lower estradiol levels were associated with night-time awakening [38]. Findings from the Study of Women's Health Across the Nation [39] indicated that lower estradiol levels and higher FSH were associated with difficulty falling asleep and remaining asleep [40]. Furthermore, these results were confirmed in later studies of polysomnographic sleep in a subgroup of SWAN participants [39].…”

Section: Discussionmentioning

confidence: 83%

The Importance of Being a ‘Lark’ in Post-Menopausal Women with Obesity: A Ploy to Prevent Type 2 Diabetes Mellitus?

et al. 2021

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Chronotype is defined as the behavioral manifestation of circadian rhythms related to the external light–dark cycle. Evening chronotype has been associated with an increased risk of developing cardiometabolic diseases in obesity. Menopause is a lifestage associated with an increased risk of developing cardiometabolic diseases and a change in circadian rhythmicity compared to pre-menopause. However, the prevalence of chronotype categories in menopause and their role in determining menopause-related cardiometabolic risk, mostly in obesity, have not been investigated. Thus, we aimed to investigate the prevalence of chronotype categories in post-menopausal women with obesity and their role in menopause-related cardiometabolic risk. In this cross-sectional study we enrolled 49 pre-menopausal and 74 post-menopausal women with obesity. Anthropometric parameters, lifestyle habits, adherence to the Mediterranean Diet (MD), sleep quality, chronotype and the presence of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) were studied. No significance differences were detected in terms of lifestyle and adherence to the MD between pre- and post-menopausal women. Chronotype was classified as morning in 66 (53.6%), evening in 20 (16.3%) and intermediate in 37 (30.1%) women. In addition, pre-menopausal women with obesity showed a significantly higher chance to have an intermediate chronotype (OR = 2.21, 95% CI 1.28–3.83; p = 0.004), whereas post-menopausal women with obesity showed a trend to have a higher morning chronotype (OR = 1.42, 95% CI 0.98–2.06; p = 0.051), although this did not reach statistical significance. No significant differences were detected in terms of prevalence of evening chronotype between the two groups. However, the evening chronotype had a significantly higher risk to have T2DM compared to the morning (OR = 17.29, 95% CI 2.40–124.27; p = 0.005) and intermediate chronotypes (OR = 30.86, 95% CI 2.05–464.32; p = 0.013) in both pre- and post-menopausal women with obesity. In conclusion, the intermediate chronotype was significantly more prevalent in pre-menopausal women with obesity compared to post-menopausal women. Evening chronotype was associated to T2DM in both pre- and post-menopause. These results support the importance of including the assessment of chronotype in the management of women with obesity in post-menopause.

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“…Similar to during the confinement period, LP is also commonly taken by Malay women postmenopause. The menopause is associated with several symptoms and mental health changes (vasomotor symptoms and cognitive function), as well as changes in physiological systems and functions (cardiovascular and bone health) (50). In rats who were given LP and oestrogen, the collagen fibres that held the adipocytes together became fragmented causing lipolysis.…”

Section: Postmenopausal Dietmentioning

confidence: 99%

Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review)

Abdullah

Mohamed

2021

Oncol Lett

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Malaysia is a developing country made up of three main ethnicities: Malay, Chinese and Indian. There are significant ethnic differences with regard to the type of daily food and cooking methods, contraception, breast-feeding preferences, confinement period and care, postmenopausal intake and influence of the traditional healer. Breast cancer is the most common cancer among Malaysian women across all three ethnicities. However, the National Cancer Registry and local medical centres have documented ethnic differences in breast cancer risk (Chinese, 40.7 per 100,000; Indian, 38.1 per 100,000; Malay, 31.5 per 100,000), peak age (youngest in the Malays), stage at presentation (largest percentage at advanced stage among the Malays) and survival (poorest survival rate among the Malays). The Malays have several practices that are protective against breast cancer compared with the Chinese. However, the Malays have strong beliefs in the traditional healer, which contribute to the delay in getting treatment, causing a poor outcome and a low survival rate. The highest BRCA1 and 2 genetic mutation incidence is amongst the Chinese, but the Malays have the largest triple-negative breast cancer rates. These factors may also contribute to the statistical breast cancer data.

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The Menopause Transition and Women’s Health at Midlife: A Progress Report From the Study of Women’s Health Across the Nation (SWAN)

Cited by 63 publications

References 109 publications

A study on women’s health information needs in menopausal age

A study on women’s health information needs in menopausal age

The Importance of Being a ‘Lark’ in Post-Menopausal Women with Obesity: A Ploy to Prevent Type 2 Diabetes Mellitus?

Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review)

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