The present study was conducted with the aim of educational SMEs in healthcare sector and mapping future developed education and training. Therefore, effects of seven pillars of 7PS model including environment, economic, social, educational, cultural, technical, and political aspects on future sustainability of educational SME for nurses have investigated. A structured questionnaire survey was conducted and multi-criteria decision making method was used to rank effects of seven pillars. The results showed that Technical, Educational and Cultural aspects have the most effect on sustainability of educational SMEs for Nurses in Iran, respectively. Accessing to educational content and analysis enables nurses deepen their knowledge that makes the technical and educational aspects of 7PS more highlight for nurses. Moreover, the Covid-19 pandemic made tele-learning and social network tools as integral component of the nurses' educational systems.