The metabolic syndrome and nonfatal ischemic heart disease; a population-based study

“…Based on a previous study, CVDs accounted for nearly 40% of mortality in Tehran, the capital city of Iran (3). A study of a random sample of 3723 subjects from an Iranian population demonstrated that 11.3% of the population had coronary symptoms and about 1.4% had experienced myocardial infarctions (3,4).…”

Section: Introductionmentioning

confidence: 99%

Association of Liver Enzymes with 10-year Cardiovascular Disease Risk: A Population-Based Study

et al. 2016

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“…The Persian Gulf Healthy Heart Study, a prospective population based cohort study, was designed to determine the risk factors for cardiovascular diseases among the northern Persian Gulf population. Detailed information about the methods and procedures of this study is available elsewhere [26].…”

Section: Patients and Controlsmentioning

confidence: 99%

Circulating levels of novel adipocytokines in patients with colorectal cancer

et al. 2013

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a b s t r a c tObjective: Adipocytokines have been reported to contribute to the pathogenesis of colorectal cancer (CRC). The aim of this matched case-control study was to explore circulating novel adipocytokines, such as serum visfatin, omentin-1 and vaspin levels in patients with CRC. Method: Serum visfatin, omentin-1, and vaspin levels were measured in 69 subjects (39 patients with colorectal cancer and 30 age-and sex-matched healthy controls) using enzyme-linked immunosorbent assay (ELISA) methods. Results: Compared with the controls, patients with CRC had significantly higher circulating omentin-1 (203.23 vs 9.12 ng/ml, p < 0.0001) visfatin (4.03 vs 2.01 ng/ml, p < 0.0001) and vaspin (0.54 vs 0.31 ng/ ml, p = 0.015) levels. After adjustment for covariates (age and body mass index), patients with CRC had significantly higher serum omentin-1 (p < 0.0001), visfatin (p < 0.0001), and vaspin (p = 0.040) levels than the control group. Furthermore, the results did not change when age and waist-to-hip ratio were considered as covariates in the general linear models. Conclusions: The observed higher levels of omentin-1, visfatin, and vaspin in patients with CRC, independent of measures of obesity, suggest that these adipocytokines may have a potential role in the development of CRC through mechanisms other than the indirect mechanisms that are active in the association between obesity and CRC.

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“…We selected an age-and sex-matched glucose-tolerant control group (49 men, 40 women, mean age 41.375 AE 9.47 years) from the Persian Gulf Healthy Heart Study participants [22] or subjects with no apparent disease history, who underwent a routine health checkup at General Clinic of Fatemeh-Zahra University Hospital. They had no family history of diabetes mellitus, type 2 diabetes or endocrine disorders, cardiovascular diseases, or hepatic or renal dysfunction and were not taking antirheumatic drugs and medications for metabolic diseases.…”

Section: Subjects and Physical Measurementsmentioning

confidence: 99%

Serum visfatin and vaspin levels in normoglycemic first-degree relatives of Iranian patients with type 2 diabetes mellitus

Akbarzadeh

Nabipour

Jafari

et al. 2012

Diabetes Research and Clinical Practice

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The metabolic syndrome and nonfatal ischemic heart disease; a population-based study

Cited by 52 publications

References 29 publications

Association of Liver Enzymes with 10-year Cardiovascular Disease Risk: A Population-Based Study

Association of Liver Enzymes with 10-year Cardiovascular Disease Risk: A Population-Based Study

Circulating levels of novel adipocytokines in patients with colorectal cancer

Serum visfatin and vaspin levels in normoglycemic first-degree relatives of Iranian patients with type 2 diabetes mellitus

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