The Metabolic Syndrome: Emerging Novel Insights Regarding the Relationship between the Homeostasis Model Assessment of Insulin Resistance and other Key Predictive Markers in Young Adults of Western Algeria

Belhayara, Mohammed Ilyes; Mellouk, Zoheir; Hamdaoui, M.; Bachaoui, M.; Khéroua, O.; Malaisse, Willy

doi:10.3390/nu12030727

Cited by 6 publications

(2 citation statements)

References 56 publications

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“…Insulin resistance was evaluated using the Homeostasis Model Assessment for Insulin Resistance (HOMA-IR), which is derived from fasting insulin and glucose. [ 19 ] An inflammatory score was used to measure the degree of inflammation in patients with type 2 diabetes. [ 20 ] Self-efficacy of diabetes was determined basing on the 7 domains of diabetes self-management as described previously.…”

Section: Methodsmentioning

confidence: 99%

The effectiveness of daily humanistic care in pharmaceutical care of patients with type 2 diabetes

Han¹,

Zhou²,

Shengxiong

et al. 2022

Medicine

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Although the current methods of pharmaceutical care have demonstrably improved pathogenic condition and humanistic health outcomes of patients with type 2 diabetes, lacking humanistic care limits its reach and effectiveness. The purpose of this study was to evaluate the effectiveness of daily humanistic care reminders in pharmaceutical care of patients with type 2 diabetes. A total of 1200 patients with type 2 diabetes were recruited. The control group received only pharmaceutical care, whereas the intervention group received extra humanistic care from clinical pharmacists. Biochemical data, levels of quality of life, satisfaction, and self-care behavior and relationships between humanistic care and glycemic control were collected before and after 12-month intervention. Humanistic care increased levels of quality of life, satisfaction, self-efficacy and self-care behavior score, decreased blood pressure, glycosylated hemoglobin A1c (HbA1c), blood lipid, fasting blood glucose, postprandial 2-h blood glucose (PPG), inflammation, and insulin resistance after 12-month follow up. Humanistic care showed a positive correlation with glycemic control and negative relationship with HbA1c in patients with type 2 diabetes. There was a positive correlation between humanistic care and glycemic control ( R = 0.641, P < .01) and a negative relationship between humanistic care and HbA1c in patients with type 2 diabetes (r = −0.482, P < .01). In conclusion, humanistic care could improve the control of overall clinical outcomes and enhanced medication adherences, which play an important role in the management of patients with type 2 diabetes.

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Section: Methodsmentioning

confidence: 99%

The effectiveness of daily humanistic care in pharmaceutical care of patients with type 2 diabetes

Han¹,

Zhou²,

Shengxiong

et al. 2022

Medicine

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show abstract

“…The prevalence depends on age, gender, race, and diagnostic criteria. The incidence of MetS is expected to increase to approximately 53% by 2035 [ 2 ].…”

Section: Concept Of Metabolic Syndromementioning

confidence: 99%

Metabolic Syndrome: Lessons from Rodent and Drosophila Models

Vatashchuk

Bayliak

Hurza

et al. 2022

BioMed Research International

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Overweight and obesity are health conditions tightly related to a number of metabolic complications collectively called “metabolic syndrome” (MetS). Clinical diagnosis of MetS includes the presence of the increased waist circumference or so-called abdominal obesity, reduced high density lipoprotein level, elevated blood pressure, and increased blood glucose and triacylglyceride levels. Different approaches, including diet-induced and genetically induced animal models, have been developed to study MetS pathogenesis and underlying mechanisms. Studies of metabolic disturbances in the fruit fly Drosophila and mammalian models along with humans have demonstrated that fruit flies and small mammalian models like rats and mice have many similarities with humans in basic metabolic functions and share many molecular mechanisms which regulate these metabolic processes. In this paper, we describe diet-induced, chemically and genetically induced animal models of the MetS. The advantages and limitations of rodent and Drosophila models of MetS and obesity are also analyzed.

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Lifestyle habits and perceived wellbeing of adults presenting with metabolic syndrome at a diabetic clinic in Ghana: A case-control study

Agbozo¹,

Bannerman²,

Klomegah³

et al. 2022

Human Nutrition & Metabolism

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The Metabolic Syndrome: Emerging Novel Insights Regarding the Relationship between the Homeostasis Model Assessment of Insulin Resistance and other Key Predictive Markers in Young Adults of Western Algeria

Cited by 6 publications

References 56 publications

The effectiveness of daily humanistic care in pharmaceutical care of patients with type 2 diabetes

The effectiveness of daily humanistic care in pharmaceutical care of patients with type 2 diabetes

Metabolic Syndrome: Lessons from Rodent and Drosophila Models

Lifestyle habits and perceived wellbeing of adults presenting with metabolic syndrome at a diabetic clinic in Ghana: A case-control study

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