The metastatic potential of head and neck cutaneous malignant melanoma: is sentinel node biopsy useful?

Main, Barry; Coyle, Margaret; Godden, Andrew; Godden, Daryl

doi:10.1016/j.bjoms.2014.01.008

Cited by 7 publications

(10 citation statements)

References 11 publications

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“…In the head and neck area, the procedure is more challenging because of the intricacy of lymphatic drainage patterns, the complexity of the local anatomy and the shine-through phenomenon [41,42]. However, an SLN detection rate of 95.2 % has been reported [43], which can be improved by additional dynamic lymphoscintigraphy [44] preoperative SPECT/CT and the intraoperative use of the gamma probe [45].…”

Section: Indicationsmentioning

confidence: 96%

EANM practice guidelines for lymphoscintigraphy and sentinel lymph node biopsy in melanoma

Bluemel

Herrmann

Giammarile

et al. 2015

Eur J Nucl Med Mol Imaging

118

131

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Section: Indicationsmentioning

confidence: 96%

EANM practice guidelines for lymphoscintigraphy and sentinel lymph node biopsy in melanoma

Bluemel

Herrmann

Giammarile

et al. 2015

Eur J Nucl Med Mol Imaging

118

131

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“…While there may be more than one SLNs that the tumor drains (45), primary tumor to be generally at a close location to the SLN may cause errors in determining the localization (46). SLN sampling is difficult in the head and neck region, due to the complex local anatomy and the shine through fenomen (the masked sentinel due to the strong radiation of the radioactive material given around the primary tumor) (47).…”

Section: Discussionmentioning

confidence: 99%

Sentinel lymph node biopsy for skin tumors

Sirvan¹,

Akgün²,

Sevim³

et al. 2016

Sisli Etfal

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patients (17 male, 13 female) aged between 21-81, who underwent SLNB, were analysed retrospectively. Results: Thirty-three SLNBs were performed in 30 patients. In all procedures sentinel lymph node was identified and excised successfully. Eight positive sentinel lymph nodes were obtained. Four patients, who had negative SLNB previously, developed symptoms on behalf of metastasis on followup, and underwent therapeutic lymph node dissection. Conclusion: Patients, who have no clinical evidence of nodal involvement but suspicion of nodal status, should undergo SLNB procedure, which has a low morbidity and complication rate. Keywords: Blue nevus, malignant melanoma, sentinel lymph node biopsy, squamous cell carcinoma, skin cancer ÖZET:Deri tümörlerinde sentinel lenf bezi biyopsisinin kullanımı Amaç: Lenf nodu tutulumu deri kanserlerinin prognozu açısından önemlidir. Klinik olarak lenf nodu tutulumu olmayan veya tutulum açısından şüpheli olan vakalarda agresif bir yöntem olan bölgesel lenf nodu disseksiyonu yerine günümüzde sentinel lenf nodu örneklemesi (SLNB) tercih edilmektedir. Çalışmamızda, kliniğimizde malign deri tümörlerine yönelik yapılan SLNB deneyimlerimizi paylaşmayı amaçladık. Gereç ve Yöntem: Ağustos 2009 ve Ağustos 2015 tarihleri arasında sentinel lenf nodu örneklemesi yapılan; yaşları 21-81 arasında değişen, 13'ü kadın, 17'si erkek, toplam 30 hasta retrospektif olarak incelendi. Bulgular: 30 hastada toplam 33 SLNB yapıldı. Tüm prosedürlerde sentinel lenf nodu (SLN) ortaya kondu ve başarılı bir şekilde eksize edildi. Toplamda 8 adet pozitif sentinel lenf nodu saptandı. Dört hastada sentinel lenf nodu örnekleme sonucu negatif olmasına rağmen, takiplerinde metastaz lehine bulgular saptanması üzerine terapötik lenf nodu disseksiyonu uygulandı. Sonuç: Klinik olarak lenf nodu tutulumu olmayan ancak tutulum açısından şüpheli olan hastalarda morbiditesi ve komplikasyon oranı daha düşük ve güvenilirliği yüksek olan, sentinel lenf nodu örneklemesi tercih edilmelidir. Anahtar kelimeler: Mavi nevüs, malign melanom, sentinel lenf nodu biyopsisi, skuamöz hücreli kanser, cilt kanseri Ş.E.E.A.H. Tıp Bülteni 2016;50(3):220-7

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“…The Multicenter Selective Lymphadenectomy Trial (MSLT-I) found that stage III patients identified through sentinel lymph node biopsy had improved survival compared to patients who developed palpable metastasis under a watchful waiting policy [41] . On the other hand, other studies have failed to show a survival advantage, leading some to question whether sentinel node biopsy provides any therapeutic benefit [45] .…”

Section: Management Of Cutaneous Melanoma Of the Head And Neck: Predimentioning

confidence: 99%

“…Approximately 13.7% of completion lymphadenectomy specimens showed evidence of additional metastatic nodes, arguing for the necessity of additional removal of lymph nodes in the setting of the discovery of micrometastatic disease. However, given the morbidity of completion lymphadenectomy, some have questioned the necessity of this additional procedure in all cases of positive sentinel nodes, especially when the initial micrometastatic nodal disease is of very low volume [45] . The MSLT-2 trial, which is currently still in progress, is seeking to address this question, comparing completion lymphadectomy for low-volume metastatic sentinel nodes versus close clinical observation, including ultrasound surveillance [50] .…”

Section: Management Of Cutaneous Melanoma Of the Head And Neck: Predimentioning

confidence: 99%

Metastatic Cancer to the Parotid

Clark

Wang

2016

Salivary Gland Neoplasms

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In many regions of the world, the most common type of parotid malignancy is metastatic malignancy. Metastatic cutaneous squamous cell carcinoma and metastatic melanoma are the most common pathologies that metastasize to the parotid gland and cervical lymph nodes. Other more rare metastatic malignancies from cutaneous primary sites include Merkel cell carcinoma, pleomorphic sarcoma (previously called malignant fibrous histiocytoma) and metastatic basal cell carcinoma. Systemic metastases can also occur from tumors such as renal cell carcinoma. This review will focus on the management of the two most common causes of parotid malignancy.

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The metastatic potential of head and neck cutaneous malignant melanoma: is sentinel node biopsy useful?

Cited by 7 publications

References 11 publications

EANM practice guidelines for lymphoscintigraphy and sentinel lymph node biopsy in melanoma

EANM practice guidelines for lymphoscintigraphy and sentinel lymph node biopsy in melanoma

Sentinel lymph node biopsy for skin tumors

Metastatic Cancer to the Parotid

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