Starting from 2,5‐bisarylidenecyclopentanone and malononitrile (1:1) several novel pyrindine derivatives were synthesized by a facile and convenient one‐pot reaction using sodium ethoxide in absolute ethanol at room temperature. The structure of the reaction products was unambiguously deduced ftom their infrared, 1H‐nuclear magnetic resonance spectroscopy, elemental analysis and single crystal X‐ray crystallography.