“…Previous studies have shown that, unlike the well-recognized most common bacteria recovered from adult acute rhinosinusitis (ARS) patients, ie, Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, 5,6 the common bacterial isolates from CRS patients are coagulase-negative Staphylococcus (CoNS), Pseudomonas aeruginosa and Staphylococcus aureus. [7][8][9][10] However, most of the published studies are descriptive studies. 7,8,[11][12][13][14][15][16][17][18] Our previous study has evaluated the associations between positive CoNS culture at functional endoscopic sinus surgery (FESS) and CRS severity, and we found that CoNS as the sole positive culture result was independently associated with having no history of FESS.…”