The Missing Umbilical Artery. I. Prospective Study Based on a Maternity Unit

Bryan, Elizabeth; Köhler, Henrik

doi:10.1097/00006254-197510000-00012

Cited by 17 publications

(36 citation statements)

References 8 publications

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“…A great proportion of the blood flow and the entire flow to the placenta runs through only one common iliac artery. It is likely that such haemodynamic variation will produce changes in vessel wall structure, and so we arranged to measure arterial distensibility in a group of children (5 to 9 years) who had been studied by Bryan and Kohler (1974), who were known to have had a single umbilical artery at birth. A non-invasive Doppler technique was used to measure pulse wave velocity, directly related to wall stiffness, and showed that there was a great difference in vessel wall behaviour on the two sides, which was still demonstrable at 9 years of age.…”

Section: Clinical Correlationmentioning

confidence: 99%

Hypertension and arterial development. Long-term considerations.

Berry¹

1978

Heart

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A considerable body of evidence supports the view that haemodynamic factors, acting during growth and development, affect the ultimate form of the larger arteries. Many of the changes induced in vessels by high pressure or flow are adaptive and effectively minimise alterations in vessel function, but these changes may predispose to degenerative disease. 'Early intervention' in arterial disease implies intervention in the first and second decades of life.

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Section: Clinical Correlationmentioning

confidence: 99%

Hypertension and arterial development. Long-term considerations.

Berry¹

1978

Heart

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“…The absence of one umbilical artery (UA), namely single umbilical artery, is one of the most common congenital malformations in the human. Absence of one UA has been noted since Renaissance times, and Gabriele Fallopio (1 523-1562) and Caspar Bahuin (1560-1624) have both been credited with its first description (Bryan and Kohler, 1974). The incidence of single UA is about 5-10/1000 singleton births, and 35-70/1000 twin births (Kleigman and Behrman, 1992).…”

Section: Introductionmentioning

confidence: 99%

Single Umbilical Artery—right or Left? Does It Matter?

et al. 1997

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Ultrasonographic prenatal diagnosis of single umbilical artery (UA) is well documented, but the exact siding of the single UA and its correlation with the occurrence of other congenital malformations and the outcome of the baby remain unclear. We report our experience with 46 cases of prenatally diagnosed single UA. This is the first prospective study of a large number of consecutive pregnancies in which the side of the existing artery was identified in fetuses with a single UA. Most of the cases were identified by transvaginal sonography at 14–16 weeks' gestation. A right artery was detected in 25 fetuses (54·3 per cent), and a left artery in 21 cases (45·7 per cent). Six fetuses (13 per cent) had associated anomalies, five of them in the urinary system. No correlation was found between the type or severity of the malformations and the side of the missing (or existing) UA. In our experience, the exact location of the single UA can be reliably determined by ultrasonography from the beginning of the second trimester of pregnancy. The selection process of the missing (or existing) vessel is likely to be random, even though a right single artery was seen slightly more often. © 1997 by John Wiley & Sons, Ltd.

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“…In the introduction to our previous paper (Bryan and Kohler, 1974) we outlined the practical problems arising from SUA. In the light of our findings we can now focus on two of these, namely (1) the detection of hidden abnormalities that may manifest themselves later on in childhood, and (2) the fate of infants who are small-for-dates at birth.…”

Section: Discussionmentioning

confidence: 99%

“…Recently we reported a study of 143 infants with a single umbilical artery (SUA) born at Leeds Maternity Hospital over a 7-year period (Bryan and Kohler, 1974). 25 of them had major congenital malformations, of whom 21 died within the first 4 weeks of life, 1 died aged 3 months, and 3 are still alive.…”

mentioning

confidence: 99%