The MMPI and Schizophrenia: A Review

Walters, Glenn D.

doi:10.1093/schbul/9.2.226

Cited by 28 publications

(19 citation statements)

References 85 publications

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“…In addition, all control candidates were interviewed and administered the Minnesota Multiphasic Personality Inventory (MMPI) by one experienced clinical psychologist (YI) in order to obtain a rather homogenous control group without eccentric profiles on the MMPI. Although the MMPI has not proved very sensitive for the detection of schizotypy (Walters, 1983), approximately 17 % of the candidates for normal control subjects were excluded for having an abnormal profile with a T-score exceeding 70. The schizophrenic comparison group comprised 40 patients with schizophrenia (20 males and 20 females; mean age = 26.1 years, SD = 5.0) in stable clinical conditions; they were identical with the schizophrenic group that was previously reported .…”

Section: Methods S Subjectsmentioning

confidence: 99%

Volumetric magnetic resonance imaging study of the anterior cingulate gyrus in schizotypal disorder

Takahashi

Suzuki

Kawasaki

et al. 2002

European Archives of Psychiatry and Clinical Neuroscience

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Lack of normal structural asymmetry of the anterior cingulate gyrus (ACG) in patients with schizophrenia has been reported in our previous study. However, to our knowledge, no morphological studies of the brain have examined changes in ACG volume in patients with schizotypal features. We investigated the volume of the gray matter and the white matter of the ACG by three-dimensional magnetic resonance imaging (MRI) in 24 patients who met the ICD-10 criteria for schizotypal disorder (12 males, 12 females) in comparison with 48 age- and gender-matched healthy control subjects (24 males, 24 females) and 40 patients with schizophrenia (20 males, 20 females). As we reported previously, right ACG gray matter volume was significantly reduced in the female patients with schizophrenia compared with the female controls. On the other hand, the gray and white matter volume of the ACG in the patients with schizotypal disorder did not differ significantly from the values in the healthy controls or the patients with schizophrenia. However, the female patients with schizotypal disorder showed a lack of right-greater-than-left asymmetry of the ACG gray and white matter found in the female controls. These results suggest that both schizotypal and schizophrenic subjects share, at least in part, the same cerebral asymmetry abnormalities.

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Section: Methods S Subjectsmentioning

confidence: 99%

Volumetric magnetic resonance imaging study of the anterior cingulate gyrus in schizotypal disorder

Takahashi

Suzuki

Kawasaki

et al. 2002

European Archives of Psychiatry and Clinical Neuroscience

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“…The following confounding variables were included as covariates * adoptee's gender, social class of the adoptive family at the time of placement, and age at MMPI assessment, since they have been shown to have effects on MMPI measures as demographic variables (57). In addition, the adoptees assessed with the MMPI were younger than the adoptees who did not complete the MMPI, and the adoptee's age was therefore used as a confounding variable.…”

Section: Methodsmentioning

confidence: 99%

Interaction of genetic vulnerability to schizophrenia and Communication Deviance of adoptive parents associated with MMPI schizophrenia vulnerability indicators of adoptees

Siira

Wahlberg

Hakko

et al. 2007

Nordic Journal of Psychiatry

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The aim of this study was to establish possible genotype-environment interaction in high-risk and low-risk adoptees' vulnerability to schizophrenia. The study population consisted of a subgroup of 41 adoptive families with a high genetic risk adoptee and 58 families with a low genetic risk adoptee from the Finnish Adoptive Family Study of Schizophrenia. Communication style was assessed based on the Communication Deviance (CD) of the adoptive parents, and the adoptees' vulnerability indicators were measured with the Minnesota Multiphasic Personality Inventory (MMPI). Taken separately, only the genetic liability to schizophrenia, but not the communication style of the adoptive parents, was significantly associated with the Lie, Correction and Hostility scales in the MMPI of the adoptees. Analyses of the genotype-environment interactions showed that the high-risk adoptees with high-CD rearing parents had an increased risk of vulnerability on the MMPI Social Maladjustment scale compared with the corresponding low-risk adoptees. Genetic vulnerability to schizophrenia and genotype-environment interaction are manifested in adoptees' MMPI.

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“…Zlunikin) for SCH of paranoid form during the acute period and the diagnosis was based upon MMPI criteria (Walters, 1983). Disease duration in this group of patients ranged between 2 months and 5 years.…”

Section: Subjectsmentioning

confidence: 99%

Dialectics and Implications of Natural Neurotropic Autoantibodies in Neurological Disease and Rehabilitation

Poletaev¹,

Абросимова²,

Sokolov³

et al. 2004

Journal of Immunology Research

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The role of natural idiotypic (Id-Abs) and anti-idiotypic (AId-Abs) autoantibodies against neuroantigens observed in different neurological disorders is not fully understood. In particular, limited experimental evidence has been provided concerning the qualitative and quantitative serological response after acute injuries of the central nervous system or during chronic mental diseases. In this study, we analyzed the specific Id-Abs and AId-Abs serological reactivities against 4 neuro-antigens in a large population of patients with ischemic stroke, schizophrenia, as well as healthy individuals.Patients with ischemic stroke were tested at different time points following the acute stroke episode and a correlation was attempted between autoantibodies response and different patterns of functional recovery. Results showed variable and detectable Id-Abs and AId-Abs in different proportions of all three populations of subjects. Among patients with different functional recovery after ischemic stroke, a difference in time-related trends of Id-Abs and AId-Abs was encountered. Our observations suggest that changes in the production of natural neurotropic Abs may engender a positive homeostatic, beside a possible pathogenic effect, in specific neurological disorders.

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The MMPI and Schizophrenia: A Review

Cited by 28 publications

References 85 publications

Volumetric magnetic resonance imaging study of the anterior cingulate gyrus in schizotypal disorder

Volumetric magnetic resonance imaging study of the anterior cingulate gyrus in schizotypal disorder

Interaction of genetic vulnerability to schizophrenia and Communication Deviance of adoptive parents associated with MMPI schizophrenia vulnerability indicators of adoptees

Dialectics and Implications of Natural Neurotropic Autoantibodies in Neurological Disease and Rehabilitation

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