The Mn-modified porphyrin metal-organic framework with enhanced oxidase-like activity for sensitively colorimetric detection of glutathione

Investigating the oxidase-like activity of a Co–Fe Prussian blue analogue nanocube prepared in situ and its applications in the colorimetric detection of ascorbic acid, alkaline phosphatase, α-glucosidase, and ascorbic acid oxidase

“…S1C (ESI†) shows the influence of different temperatures on the oxidase-like activity of the Co–Fe PBA NC, indicating that the temperature (20–60 °C) has no significant influence on the catalytic activity. Notably, unlike most other oxidase mimics, 25–27 the catalytic activity of the Co–Fe PBA NC remains stable in a wide temperature range, showing its excellent high temperature tolerance, which can also allow the detection of analytes at room temperature. For the practical application, 30 °C was chosen as the optimal reaction temperature.…”

Single-atom nanozymes: From bench to bedside

“…In vitro experiment proved the satisfactory sensitivity and specificity of Fe-N-C SAN for the quantitative determination of H 2 O 2 . For practical applications, the authors also performed a quantitative determination of H 2 O 2 produced from the Hela cells with Fe-N-C SAN [115].…”

Tetrabutylammonium-chloride-glycerol of deep eutectic solvent functionalized MnO2: a novel mimic enzyme for the quantitative and qualitative colorimetric detection of l-cysteine

“…In recent years, due to the advantages of its simple operation, there is no need for expensive instruments, visible detection by the naked eye, and the nanozyme-based colorimetric method has gradually attracted increasing attention and has been widely used in the field of analysis and detection. 7 To date, research on the reported oxidase mimics as colorimetric materials has mainly focused on metal nanoclusters/nanoparticles, 8,9 metal–organic frameworks, 10 graphene oxide, 11 iron oxides, 12 carbon dots, 13 etc . MnO 2 nanosheet, a type of transition metal oxide, has low toxicity and good biocompatibility, rich redox chemistry, and excellent catalytic and oxidase-like activity.…”