We have proved that the chemical reaction induced by femtosecond laser filament in the atmosphere produces CO, HCN and NO, and the production CO and HCN were observed for the first time. The concentrations of the products were measured by mid-infrared tunable laser absorption spectroscopy. In reduced pressure air, the decomposition of CO2 was enhanced by vibration excitation induced by laser filament, resulting in enhanced production of CO and HCN. At the same time, the generated CO and HCN from the atmosphere suffered rotation excitation induced by laser filament, enhancing their absorption spectra. We found NO, CO, and HCN accumulating to 134 ppm, 80 ppm, and 1.6 ppm in sealed air after sufficient reaction time. The atmospheric chemical reaction induced by laser filament opens up a way to change the air composition while maintaining environmental benefits.