The Model for End-Stage Liver Disease Score-Based System Predicts Short Term Mortality Better Than the Current Child-Turcotte-Pugh Score-Based Allocation System during Waiting for Deceased Liver Transplantation

Hong, Geun; Lee, Kwang Woong; Suh, Soo Jhi; Yoo, Tae Kyung; Kim, Hyeyoung; Park, Min Su; Choi, Young Rok; Suh, Kyung Suk

doi:10.3346/jkms.2013.28.8.1207

Cited by 24 publications

(21 citation statements)

References 16 publications

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“…The CTP scoring system, with a total of 15 points, has a relatively narrow grading range, and its assessment indicators of ascites and hepatic encephalopathy are strongly subjective, lacking objective quantification (8). The indicators of the MELD scoring system are all objective, and the inclusion of creatinine (Cr) reflects the effect of complicating hepatorenal syndrome on the prognosis of LC patients to a certain extent (9). However, the MELD score is typically significantly affected by large variations in the international normalized ratio (INR) due to measurement by different laboratories with different methods (10).…”

Section: Introductionmentioning

confidence: 99%

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

et al. 2018

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Abstract. The aim of the present study was to investigate the value of the albumin-bilirubin (ALBI) score in the assessment of the disease conditions of hepatitis B virus (HBV)-related acute-on-chronic liver failure (HBV-ACLF), HBV-related liver cirrhosis (HBV-LC) and HBV-related hepatocellular carcinoma (HBV-HCC). A total of 395 patients with HBV-ACLF, HBV-LC, or HBV-HCC were retrospectively studied. The ALBI, Child-Turcotte-Pugh (CTP), and Model for End-Stage Liver Disease (MELD) scores of the patients were calculated, and the relationships between the ALBI score and the CTP and MELD scores were investigated. Furthermore, the ALBI grading was tested for the evaluation of the severity and stages of HBV-ACLF, HBV-LC, and HBV-HCC, especially when classifying the clinical stages of HBV-ACLF. The mean ALBI scores of the HBV-ACLF, HBV-LC, and HBV-HCC patients were -1.17±0.55, -1.76±0.66 and -2.59±0.62, respectively; the mean CTP scores were 10.70±1. 81, 8.19±1.25 and 5.81±1.22, respectively; and the mean MELD scores were 19.93±7.44, 11.10±4.39 and 7.01±3.22, respectively. The ALBI scores were positively correlated with the CTP and MELD scores. The mean ALBI score and the frequency of grade 3 disease were higher in HBV-ACLF patients than in patients with HBV-LC or HBV-HCC. A later HBV-ACLF stage resulted in a higher frequency of ALBI grades of 3. In conclusion, ALBI scores exhibited parallel tendencies to the CTP and MELD scores in HBV-ACLF, HBV-LC, and HBV-HCC patients; thus, ALBI grading may be a simple but applicable method for the evaluation of the functional status of patients with HBV-related end-stage liver diseases.

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Section: Introductionmentioning

confidence: 99%

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

et al. 2018

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“…MELD has been validated as a predictor of wait-list mortality in transplantation candidates and has been postulated as a predictor of posttransplant survival. [41][42][43] A systematic review and critical appraisal was performed using Cochrane guidelines. There were 3,058 discrete citations identified and screened for possible inclusion.…”

Section: Procurement and Transplant Aligned Inside Hospital Pathwaysmentioning

confidence: 99%

Organizational determinants in the procurement and transplantation pathway: a review

Triassi¹,

Giancotti²,

Nardone³

et al. 2014

TRRM

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Introduction:The growing disparity between organ availability for transplantation and the number of patients in need has challenged the donation and transplantation community to develop innovative processes, ideas, and techniques to bridge this gap. Advances in the sharing of best practices in the donation community have contributed greatly to this aim over the past 5 years. Studies published during the past five years (2010-2014) were analyzed to gain insight on the evolving organizational areas and tools that the procurement and transplantation pathways have been focused on. The hypothesis assessed is that networking and efficacious handling of this complex path may be ameliorated by an adaptive organizational toolbox. Methods: A thorough search has been conducted using various databases, ie, Cochrane library, PubMed, EMBASE, Federico II University Open Archive. The evidence was considered following the Effective Practice and Organization of Care Group checklist. Prevalent organizational attitudes and areas were assessed, and various scenarios were analyzed. Initially, all titles and abstracts were screened. In the next phase, the full text of all abstracts considered potentially relevant by at least one of the reviewers was evaluated. Inconsistencies in decision-making within this second phase were solved based on consensus between both reviewers. In this phase, for every study we defined whether the organization was considered relevant and what the scenario was. The information was extracted from each study based on bibliographic details (author, journal, year of publication, and language). As many as 1,071 studies were analyzed, and 81 were selected as potentially relevant. Results: We found three prevalent areas of interest focused on organizational elements: global organizational strategies scenario, clinical hospital organization, and citizenship and social scenario. Conclusion: We reached the conclusion that organization has a central role in different scenarios of procurement and transplantation in a continuum from government to hospital (the core of the system) and finally among citizens. A standardized hospital pathway definitely remains the essential step in order to ameliorate either procurement or transplantation.

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“…The Child–Pugh–Turcotte (CPT) classification and the model of end‐stage liver disease (MELD) score are the most commonly used for patient priority on the waiting list of liver transplantation . Modifications of MELD score have been proposed to improve the predictive value . MELD serum sodium (MELD‐Na) score presented promising value for predicting mortality among patients on the liver‐transplant waiting list .…”

Section: Introductionmentioning

confidence: 99%

Performance of scoring systems to predict mortality of patients with acute‐on‐chronic liver failure: A systematic review and meta‐analysis

Zheng

Zhong

et al. 2017

J of Gastro and Hepatol

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The Model for End-Stage Liver Disease Score-Based System Predicts Short Term Mortality Better Than the Current Child-Turcotte-Pugh Score-Based Allocation System during Waiting for Deceased Liver Transplantation

Cited by 24 publications

References 16 publications

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

Value of the albumin‑bilirubin score in the evaluation of hepatitis B virus‑related acute‑on‑chronic liver failure, liver cirrhosis, and hepatocellular carcinoma

Organizational determinants in the procurement and transplantation pathway: a review

Performance of scoring systems to predict mortality of patients with acute‐on‐chronic liver failure: A systematic review and meta‐analysis

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