The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests

Slavík, Luděk; Úlehlová, Jana; Bradacova, P; Chasakova, K.; Hluší, Antonín; Palová, Miroslava; Entrová, Alice

doi:10.1007/s10916-020-01614-6

Cited by 9 publications

(5 citation statements)

References 14 publications

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“…Past investigations suggest that rapid accelerations (multiples of gravitational force) in PTS are significantly positively correlated with the degree of haemolysis [18]. Mullins et al [19] demonstrated that a longer duration of forceful acceleration tended to increase the HI and plasma LDH in blood samples after they were transported by PTS routes.…”

Section: Discussionmentioning

confidence: 99%

“…Le Quellec et al [16] found a statistically significant shortening of the APTT and an increase in D-dimer levels after blood sample transport by the PTS. In addition, Slavík et al [18] showed that, despite no obvious effect on basic coagulation test results, PTS transportation with a speed of 6 m/s, to some extent, resulted in a statistically significant difference in the use of the thrombin generation test (TGT) as a sensitive monitoring method. However, our results showed that for the delivery of FFP or cryoprecipitate, there was no significant difference in the value of routine haematology and coagulation parameters, including PT, PT-INR, APTT, TT and FIB, between the specimens tested before and after RLTS transport.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of a rail logistics transmission system for the transportation of blood components within a medical centre

Chen,

Zang,

Wang

et al. 2023

Vox Sanguinis

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Background and ObjectivesRail logistics transmission systems (RLTSs) are commonly used for the transportation of blood samples, pathological specimens and other medical materials in many hospitals, as they are rapid, secure, cost‐effective and intelligent. However, few studies have evaluated blood component transportation from blood banks to the patient care areas of hospitals using RLTS. In this study, we evaluate the RLTS used for the transportation of blood components within a medical centre.Materials and MethodsThe dispatch of blood components, including packed red blood cells (pRBCs), fresh frozen plasma (FFP), cryoprecipitate and platelet units, from a blood bank to critical care areas or general wards was done using RLTS. Parameters such as the delivery time, temperature, physical integrity and blood component quality were evaluated via analytical testing using specimens obtained before and after transportation by RLTS.ResultsThe turnaround time and temperature of all tested blood units via RLTS transportation were able to meet the clinical demands of blood component delivery (median time: 323 s [118–668 s]; temperature variation: 4.5–8.9°C for pRBCs and FFP and 21.5–23.5°C for cryoprecipitate and platelet units). Furthermore, parameters of pRBC quality, including the haemolysis index and potassium and lactate dehydrogenase levels in plasma, were not significantly different before and after transportation through RLTS. Similarly, RLTS transportation affected neither the basic coagulation test results in FFP and cryoprecipitate specimens nor platelet aggregation and activation markers in apheresis platelet specimens.ConclusionHospital‐wide delivery of blood components via RLTS seems to be safe, reliable and cost‐effective and does not have any negative impact on blood quality. Therefore, the establishment of standard criteria, protocols and guidelines based on further studies is needed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of a rail logistics transmission system for the transportation of blood components within a medical centre

Chen,

Zang,

Wang

et al. 2023

Vox Sanguinis

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“… 31 , 32 However, modern PTS dispose regulated transport speed with an acceleration control. 33 Before transporting apheresis platelet concentrates via the PTS, acceleration forces should be measured at each facility and validation using a quality threshold should be performed. 9 , 19 , 34 An appropriate study design for this is provided by Garcia et al 35 or by Stangerup et al 36 who performed a 5‐day validation using mini data logger.…”

Section: Discussionmentioning

confidence: 99%

“…In particular, using a three‐axis accelerometer offers the opportunity to record a combination of acceleration, magnitude of force, and duration of the transport 31,32 . However, modern PTS dispose regulated transport speed with an acceleration control 33 . Before transporting apheresis platelet concentrates via the PTS, acceleration forces should be measured at each facility and validation using a quality threshold should be performed 9,19,34 .…”

Section: Discussionmentioning

confidence: 99%

Triple apheresis platelet concentrate quality after pneumatic tube system, conveyor box, and courier transport: An observational study

Reichert

Wallner

Burkhardt

et al. 2022

Health Science Reports

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Background and Aims Platelets are prone to activation from handling; they are therefore transported as gently as possible, most commonly by courier. Speedier methods like pneumatic tube system (PTS) transport could improve patient care but may subject platelets to mechanical stress. To test the impact of mechanical stress caused by transport, we compared a PTS with a conveyor box and courier transport on apheresis platelet function. Methods Fourteen apheresis platelet concentrate triple donations were analyzed by light transmission aggregometry (LTA), rotational thrombelastometry (ROTEM), and flow cytometry before and after indoor transport over 800 m by PTS, conveyor, and courier, respectively, while recording shocks and vibrations with a high‐frequency acceleration data logger. Shock index scores were calculated as shock intensity (g‐force) times frequency. Results The shock index was 81 for courier, 6279 for conveyor, and 9075 for PTS. Flow cytometry revealed no significant difference in platelet surface expression of CD62p before (16%) and after transport via courier (15%), conveyor (14%), or PTS (16%). LTA with adenosine phosphate and thrombin receptor‐activating peptide‐6 resulted in comparable platelet aggregation for courier, conveyor, and PTS. ROTEM assays showed no relevant differences in coagulation time, clot formation time, and maximum clot firmness between transport modes. Conclusion Though the mechanical challenge was smallest with courier transport, there were no significant differences in platelet activation or aggregation between the three transport modes. These data contradict restrictions on the use of PTSs for platelet concentrate transport.

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“…This work is the "Simulation analysis of pneumatic tube system". One of the most recent literature to be found is "The Modern Pneumatic Tube System Transport with Reduced Speed Does Not Affect Special Coagulation Tests" by L. Slavík et al published in 2020, which investigates whether blood samples are not damaged when they are transported by the pneumatic tube system for evaluation [19].…”

Section: Application Of Pneumatic Tube Systemmentioning

confidence: 99%

Improving the Logistics of Institutional Postal Services

Nagy,

Bányai

2023

ALS

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Postal services are often considered by the different institutions as a back-up service. Taking into account that in case of large geographical coverage these services can generate significant costs, it is important to optimize the postal service functions within these institutions and to develop the already existing conventional postal services. Within the frame of this article the authors review the logistics processes of the postal services at the University of Miskolc to propose improvements to the processes of postal services focusing on delivery. The main regulatory elements and the logistics processes of the institutional postal services are discussed and some critical remarks are described focusing on three main areas: the facility location optimization of the institutional postal services, the lack of use of modern technologies and the lack of modern administrative facilities. On the basis of these criticisms, the authors define recommendations for improving institutional postal services. Regarding the facility location optimization problem, a mathematical model and an optimization algorithm is described to evaluate the efficiency of the logistics processes of delivery services. The proposed methodology supports a cost-based analysis of different solution variants and a priority-based differentiation between institutions and offices. The suggested approach is tested with a real scenario, where the numerical results validate the efficiency of the evaluation of optimization algorithm. The second improvement direction is the application of a pneumatic tube system. The authors show the most important parts of the proposed pneumatic tube system, which can lead to decreased labor cost and increased service level.

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The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests

Cited by 9 publications

References 14 publications

Evaluation of a rail logistics transmission system for the transportation of blood components within a medical centre

Evaluation of a rail logistics transmission system for the transportation of blood components within a medical centre

Triple apheresis platelet concentrate quality after pneumatic tube system, conveyor box, and courier transport: An observational study

Improving the Logistics of Institutional Postal Services

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