The modified norwood procedure for hypoplastic left heart syndrome: Early to intermediate results of 120 patients with particular reference to aortic arch repair

Ishino, Kozo; Stümper, Oliver; Giovanni, Joseph J.V. De; Silove, Eric D.; Wright, John; Sethia, B; Brawn, William J.

doi:10.1016/s0022-5223(99)70373-9

Cited by 173 publications

(122 citation statements)

References 20 publications

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“…One of the most frequently employed techniques for aortic arch reconstruction includes the use of pulmonary homografts, but they are expensive, difficult to obtain, and immunologic sensitization may lead to further problems if heart transplantation is required 12,17,18 . Direct aortic anastomosis is technically more complex and cannot always be performed, although no difference is observed in relation to homologous grafts as for the need for aortic arch reintervention [19][20][21][22] .…”

Section: Discussionmentioning

confidence: 99%

Síndrome da hipoplasia do coração esquerdo: a influência da estratégia cirúrgica nos resultados

Silva¹,

Fonseca²,

Baumgratz³

et al. 2007

Arq. Bras. Cardiol.

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SummaryObjectives: To report a surgical strategy for the Norwood procedure in the hypoplastic left heart syndrome (HLHS) that enables short hypothermic circulatory arrest time and aortic arch reconstruction with autologous pericardium patch, and to compare the results of the modified Blalock- Taussig Results: In-hospital survival for the entire cohort was 74.64%, or 67.57% and 82.35% for the mBT shunt and RV-PA conduit groups, respectively (p=0.1808). Mortality rates between the first and second palliation stages were 40% and 4.4% for the mBT shunt and RV-PA conduit groups, respectively (p=0.0054). Hypothermic circulatory arrest times were 45.79±1.99 min and 36.62±1.62min (p=0.0012), respectively. Late coarctation of the aorta occurred in five patients (7.2%).Conclusions: This surgical strategy resulted in short circulatory arrest time, low mortality and favorable morphology of the neoaorta, with low incidence of late coarctation of the aorta. The higher rate of survival to first palliation stage with the RV-PA conduit was not significant, but interstage mortality was statistically lower when compared with the modified Blalock-Taussig shunt procedure.

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Section: Discussionmentioning

confidence: 99%

Síndrome da hipoplasia do coração esquerdo: a influência da estratégia cirúrgica nos resultados

Silva¹,

Fonseca²,

Baumgratz³

et al. 2007

Arq. Bras. Cardiol.

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“…In the Birmingham series, infants undergoing a Norwood operation had an actuarial 4-year survival of 44%. 19 In another report from the same centre there was a 25% 6-month survival among live-born affected infants and a 15% 6-month survival (taking into account termination of pregnancy) in infants diagnosed antenatally. 20 In a recent report from Guy's Hospital, only one-third of antenatally diagnosed infants were live-born and 50% of the latter survived the first stage of palliation.…”

Section: Outcomementioning

confidence: 93%

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Knowles¹,

Griebsch²,

Dezateux

et al. 2005

Health Technol Assess

214

143

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“…Moreover, these grafts may cause future problems if heart transplantation is necessary [16,23]. The direct anastomosis of the aorta is technically more complex and not always feasible, even though no significant differences have been reported between this technique and homologous grafts in respect to the necessity of reinterventions of the aortic arch [5,6,8].…”

Section: Braz J Cardiovasc Surg 2007; 22(2): 160-168mentioning

confidence: 99%

“…Reconstruction of the aortic arch, initially performed using PTFE [3], can also be achieved with other prosthetic materials (Dacron, bovine pericardium) or without using additional materials [4,5], however there is a high incidence of re-coarctation [6,7]. Homologous pulmonary grafts are the most commonly used materials for reconstruction however they induce the formation of antibodies [8] and are very expensive.…”

Section: Introductionmentioning

confidence: 99%

Síndrome do coração esquerdo hipoplásico: estratégia cirúrgica e comparação de resultados com técnicas de Norwood x Sano

Silva¹,

Fonseca²,

Baumgratz³

et al. 2007

Rev Bras Cir Cardiovasc

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The modified norwood procedure for hypoplastic left heart syndrome: Early to intermediate results of 120 patients with particular reference to aortic arch repair

Cited by 173 publications

References 20 publications

Síndrome da hipoplasia do coração esquerdo: a influência da estratégia cirúrgica nos resultados

Síndrome da hipoplasia do coração esquerdo: a influência da estratégia cirúrgica nos resultados

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Síndrome do coração esquerdo hipoplásico: estratégia cirúrgica e comparação de resultados com técnicas de Norwood x Sano

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