2024
DOI: 10.1042/bst20230403
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The molecular mechanisms driving Plasmodium cell division

David S. Guttery,
Mohammad Zeeshan,
Anthony A. Holder
et al.

Abstract: Malaria, a vector borne disease, is a major global health and socioeconomic problem caused by the apicomplexan protozoan parasite Plasmodium. The parasite alternates between mosquito vector and vertebrate host, with meiosis in the mosquito and proliferative mitotic cell division in both hosts. In the canonical eukaryotic model, cell division is either by open or closed mitosis and karyokinesis is followed by cytokinesis; whereas in Plasmodium closed mitosis is not directly accompanied by concomitant cell divis… Show more

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