-The paper deals with some tasks of advanced methods to achieve security and reliability of transmission power systems. There are discussed advanced principles and techniques in monitoring systems. The paper main part is devoted to possible applications of PMUs (Phasor Measurement Unit) and their integration into WAMPaC systems (Wide Area Monitoring, Protection and Control). Significant transmission system states were analyzed in several case studies. PMUs utilization for voltage monitoring is demonstrated for three cases -standard system state, high-load state and islanding. Here the attention is paid to the possibilities of power system observability improvement using measuring chain error elimination. Other possible applications in transmission systems include ampacity determination of transmission corridors, the calculation of line electrical parameters using synchrophasor measurement, state estimation issues and power system stability. The power system model was established for methods and algorithms verification purposes. The appropriate algorithms and their parameters were found using simulation outputs to create the local automatics, e.g. Automatic Power System Stabilizer (PSS).