The Monte Carlo Method of Mixed Radiation Field Dose Assessment in the Cytogenetic Biodosimetry

Powojska, Aleksandra; Słonecka, Iwona; Fornalski, Krzysztof W.

doi:10.12693/aphyspola.134.583

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…In principle, these tables can be read by any radiation transport code; in this work, they were read by FLUKA, exploiting a pre-existing interface between the two codes and taking into account that space radiation is a mixed field involving different particles and different energy values. Several ways exist to deal with the effects of mixed fields [46]; in this work, whenever according to FLUKA a certain amount of energy (and thus a certain dose, D i ) was deposited in a target voxel by a given radiation type i (where "radiation type" means a given particle of given energy, and thus given LET), FLUKA read from the tables the corresponding coefficients (α i and β i for cell survival; a i and b i for lymphocyte dicentrics) and used them to calculate the average coefficients describing the fraction of surviving cells (called α and β) or those describing the yield of dicentrics (called a and b), due to the mixed field in that voxel.…”

Section: Rbe Calculation By Means Of the Bianca Biophysical Modelmentioning

confidence: 99%

A Mission to Mars: Prediction of GCR Doses and Comparison with Astronaut Dose Limits

Ramos

Carante

Ferrari

et al. 2023

IJMS

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Long-term human space missions such as a future journey to Mars could be characterized by several hazards, among which radiation is one the highest-priority problems for astronaut health. In this work, exploiting a pre-existing interface between the BIANCA biophysical model and the FLUKA Monte Carlo transport code, a study was performed to calculate astronaut absorbed doses and equivalent doses following GCR exposure under different shielding conditions. More specifically, the interface with BIANCA allowed us to calculate both the RBE for cell survival, which is related to non-cancer effects, and that for chromosome aberrations, related to the induction of stochastic effects, including cancer. The results were then compared with cancer and non-cancer astronaut dose limits. Concerning the stochastic effects, the equivalent doses calculated by multiplying the absorbed dose by the RBE for chromosome aberrations (“high-dose method”) were similar to those calculated using the Q-values recommended by ICRP. For a 650-day mission at solar minimum (representative of a possible Mars mission scenario), the obtained values are always lower than the career limit recommended by ICRP (1 Sv), but higher than the limit of 600 mSv recently adopted by NASA. The comparison with the JAXA limits is more complex, since they are age and sex dependent. Concerning the deterministic limits, even for a 650-day mission at solar minimum, the values obtained by multiplying the absorbed dose by the RBE for cell survival are largely below the limits established by the various space agencies. Following this work, BIANCA, interfaced with an MC transport code such as FLUKA, can now predict RBE values for cell death and chromosome aberrations following GCR exposure. More generally, both at solar minimum and at solar maximum, shielding of 10 g/cm2 Al seems to be a better choice than 20 g/cm2 for astronaut protection against GCR.

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Section: Rbe Calculation By Means Of the Bianca Biophysical Modelmentioning

confidence: 99%

A Mission to Mars: Prediction of GCR Doses and Comparison with Astronaut Dose Limits

Ramos

Carante

Ferrari

et al. 2023

IJMS

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“…In such situations, Bayesian statistics as well as the Monte Carlo methods, which were successfully applied in mixed neutron-gamma radiation fields for biological dosimetry (Brame and Groer 2003 ; Ainsbury et al 2013a , b ; Pacyniak et al 2014 ; Słonecka et al 2019 ; Powojska et al 2018 ), may be useful. The present paper develops the Bayesian method further, supported by Monte Carlo calculations, as an alternative and very appropriate tool supporting mixed beta-gamma TL dosimetry.…”

Section: Introductionmentioning

confidence: 99%

Application of Bayesian statistics for radiation dose assessment in mixed beta-gamma fields

Słonecka

Krasowska

Baranowska

et al. 2021

Radiat Environ Biophys

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The present paper proposes a novel method, based on Bayesian statistics, as a new approach in the field of thermoluminescence dosimetry for the assessment of personal doses in mixed beta-gamma radiation fields. The method can be utilized in situations when the classical way of dose calculation is insufficient or impossible. The proposed method uses a prior function which can be assigned to the unknown parameter and the likelihood function obtained from an experiment, which together can be transformed into the posterior probability distribution of the sought parameter. Finally, the distribution is converted to the value of the dose. The proposed method is supported by analytical and Monte Carlo calculations, which confirmed the results obtained through the Bayesian approach.

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Simplified Bayesian method: application in cytogenetic biological dosimetry of mixed n + γ radiation fields

Słonecka

Łukasik

Fornalski

2018

Radiat Environ Biophys

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This article describes the application of a simplified Bayesian method for estimation of doses from a mixed field using cytogenetic biological dosimetry, taking as an example neutron and gamma radiation emitted from the MARIA nuclear research reactor in Poland. The Bayesian approach is a good alternative to the commonly used iterative method, which allows separate dose estimation. In the present paper, a computer program, which uses the iterative and simplified Bayesian methods to calculate mixed radiation doses, is introduced.

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The Monte Carlo Method of Mixed Radiation Field Dose Assessment in the Cytogenetic Biodosimetry

Cited by 3 publications

References 6 publications

A Mission to Mars: Prediction of GCR Doses and Comparison with Astronaut Dose Limits

A Mission to Mars: Prediction of GCR Doses and Comparison with Astronaut Dose Limits

Application of Bayesian statistics for radiation dose assessment in mixed beta-gamma fields

Simplified Bayesian method: application in cytogenetic biological dosimetry of mixed n + γ radiation fields

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