The Montreal Cognitive Assessment in Persons with Traumatic Brain Injury

Guise, Élaine de; Alturki, Abdulrahman Y.; LeBlanc, Joanne; Champoux, Marie-Claude; Couturier, Céline; Lamoureux, Julie; Desjardins, Marie‐Pier; Marcoux, Judith; Maleki, Mohammed; Feyz, Mitra

doi:10.1080/09084282.2013.778260

Cited by 58 publications

(35 citation statements)

References 37 publications

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“…45 Additionally, testing using the MoCA in other patient populations has not shown a sex difference. 23,24,30,46 In our study, an equal proportion of males (45%) and females (46%) had a history of one or more concussions, and males were not more likely to have three or more of SRC. When comparing male athletes only, no significant difference was found between contact/collision sports and no/limited contact sport athletes (26.4 ± 2.1 vs. 26.8 ± 2.1; p = 0.49), and a previous medical history of migraine, ADHD, anxiety, and depression did not influence the results.…”

Section: Sex Difference In Moca Scoresmentioning

confidence: 45%

“…21,[23][24][25][26][27][28][29] Most recently, three studies have administered the MoCA to patients with mild traumatic brain injury/concussion and found there was a relationship between severity of injury and lower scores on the MoCA. [30][31][32] The authors concluded that the MoCA was a useful cognitive screening tool for patients with mild to severe traumatic brain injury (TBI).…”

Section: Introductionmentioning

confidence: 99%

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The Montreal Cognitive Assessment as a Cognitive Screening Tool in Athletes

Debert

Stilling

Wang

et al. 2019

Can. J. Neurol. Sci.

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ABSTRACT:Background: The Montreal Cognitive Assessment (MoCA) is a cognitive screening tool known to accurately measure mild cognitive impairment (MCI) in many different neurological populations. Objective: We aimed to determine whether a sport-related concussion (SRC) history and other concussion modifiers influence global cognitive function in high-performance athletes. Methods: A cross-sectional study of 326 varsity and national team athletes aged 18–36 years was completed at the University of Calgary Sports Medicine Clinic, Calgary, Alberta, Canada. Logistic regression analysis was used to examine the association between the total MoCA score, MoCA subscales, and number of previous SRC, adjusting for age, sex, sport participation (SP), and concussion modifiers. Results: Athletes with a history of three or more SRC were 5.36 times more likely to score less than 26/30 on the MoCA (the cutoff for MCI) compared to athletes with two or less SRC (p = 0.02). Males were 2.23 times more likely to have MCI than females (p = 0.0004). There was a significant relationship between the number of previous concussions and the MoCA subscales of attention (p = 0.05) and abstraction (p = 0.003). Age, SP, and concussion modifiers (migraine, depression, anxiety, and attention deficit and hyperactivity disorder) did not influence the relationship between MoCA and previous concussion history. Conclusion: In the appropriate clinical context, cognitive screening with the MoCA may benefit clinical care in athletes with multiple previous SRC, but should not replace a full neuropsychological assessment. Thus, further research is needed to compare the MoCA to full neuropsychological assessments in this population.

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Section: Sex Difference In Moca Scoresmentioning

confidence: 45%

Section: Introductionmentioning

confidence: 99%

The Montreal Cognitive Assessment as a Cognitive Screening Tool in Athletes

Debert

Stilling

Wang

et al. 2019

Can. J. Neurol. Sci.

View full text Add to dashboard Cite

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“…In this study, either the English or the Spanish version was used. [10][11] The alternative versions were used twice across assessments (in the following order: 1, 2, 3, 1, 2, 3).…”

Section: Bloodmentioning

confidence: 99%

“…Subsequently, all epochs were averaged, and the mean of the power spectral density in different frequency bands were exported for statistical analysis. Frequency bands were chosen at target electrode sites based on previous literature pinpointing sites of maximal amplitude for each band: alpha(8)(9)(10)(11)(12)(13) at the occipital electrodes (O1, Oz, O2), theta (4-7 Hz) at the frontal electrodes (F7, F3, Fz, F4, F8), and delta (1-3 Hz) at the central electrodes (C3, Cz, C4). The averaged power spectral density extracted for each site (F, C, O) was expressed in absolute power (μV2) [22].…”

mentioning

confidence: 99%

Longitudinal changes in blood-based biomarkers in chronic moderate to severe traumatic brain injury: preliminary findings

Schnakers

Divine

Johnson

et al. 2019

Preprint

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Background Little is known about the changes in blood-based biomarkers and their relation to outcome, years after TBI. This prospective study aims to provide preliminary evidence of longitudinal changes blood-based biomarkers that relate to changes in outcome measures and cerebral structure and activity.Methods Eight patients with moderate-to-severe TBI were recruited (7 males, 35 ± 7.6 years old, 5 severe TBI, 17.52 ± 3.84 months post-injury). The following data were evaluated at monthly intervals across 6 time-points: a) Blood-based biomarkers, including GFAP, NSE, S100A12, SDBP145, UCH-L1, T-tau, P-tau, and P-tau/T-tau ratio; b) Magnetic Resonance Imaging (MRI) to evaluate changes in brain structure using FMRIB Software Library (FSL); c) Resting state electroencephalograms (EEG) to evaluate changes in brain function using EEGLAB; and d) Outcome measures to assess cognition, emotion and functional recovery (i.e., MOCA, RBANS, BDI-II and DRS).Results Changes in P-tau levels were found across time [p=0.007]. P-tau was positively related to functional [p<0.001] and cognitive [p=0.006] outcomes, and negatively related to the severity of depression, 6 months later [R=-0.901; p=.006]. P-tau and P-tau/T-tau ratio were also positively correlated to shape change in subcortical areas such as brainstem [T(7)=4.71, p=0.008] and putamen [T(7)=3.25, p = 0.012].Conclusions Our study provides preliminary findings that suggest a relationship between P-tau and the recovery of patients with chronic TBI. Further investigation in a larger cohort is warranted to validate this biomarker and better understand the mechanism of neural recovery in chronic patients.

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“…Hasil penelitian ini sama dengan data dari salah satu rumah sakit di Jakarta, RS Cipto Mangunkusumo dimana kejadian cedera kepala tertinggi ialah cedera kepala ringan. 10 Hasil…”

Section: Bahasanunclassified

Gambaran skor MMSE dan MoCA-INA pada pasien cedera kepala ringan dan sedang yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado

Athika¹,

Ps²,

Mawuntu³

2016

eCl

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Traumatic Brain Injury (TBI) is the most common case in hospital. TBI can caused cognitive impairment. This study aimed to obtain the description of cognitive function in patients with mild and moderate TBI that were admitted to Prof. Dr. R. D. Kandou Hospital Manado. This was a prospective descriptive study by conducting direct examination to the patients diagnosed with mild or moderate TBI by using MMSE and Ina MoCA instruments. Thee results showed that there of 50 subjects there were 74% with mild TBI and 26% with moderate TBI. MMSE showed 96% normal while Ina MoCA showed 76% normal. Cognitive function impairment was more visible on Ina MoCA examination. Conclusion: Ina MoCA was better than MMSE examination in description of cognitive function impairment.Keywords: head injury, cognitive function Abstrak: Cedera kepala merupakan suatu kegawatan yang paling sering dijumpai di Rumah Sakit. Cedera kepala dapat menyebabkan gangguan fungsi kognitif. Penelitian ini bertujuan untuk mengetahui gambaran skor MMSE dan MoCA-Ina pada pasien cedera kepala ringan dan sedang yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ini ialah deskriptif prospektif dengan melakukan pemeriksaan langsung pada pasien yang didiagnosis cedera kepala ringan atau sedang menggunakan instrumen MMSE dan MoCA-Ina. Hasil penelitian mendapatkan subjek sebanyak 50 orang dengan persentase cedera kepala ringan sebanyak 74% dan cedera kepala sedang 26%. Pada MMSE didapatkan 96% normal sedangkan pada MoCA-Ina didapatkan 76% normal. Penurunan fungsi kognitif lebih terlihat pada pemeriksaan MoCA-Ina. Simpulan: MoCA-Ina lebih dapat menggambarkan gangguan fungsi kognitif daripada pemeriksaan MMSE. Kata kunci: cedera kepala, fungsi kognitif

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The Montreal Cognitive Assessment in Persons with Traumatic Brain Injury

Cited by 58 publications

References 37 publications

The Montreal Cognitive Assessment as a Cognitive Screening Tool in Athletes

The Montreal Cognitive Assessment as a Cognitive Screening Tool in Athletes

Longitudinal changes in blood-based biomarkers in chronic moderate to severe traumatic brain injury: preliminary findings

Gambaran skor MMSE dan MoCA-INA pada pasien cedera kepala ringan dan sedang yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado

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