The morphology of the human mandible: A computational modelling study

Vallabh, Ravin; Ju, Zhang; Fernandez, Justin; Dimitroulis, George; Ackland, David C.

doi:10.1007/s10237-019-01133-5

Cited by 38 publications

(23 citation statements)

References 48 publications

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“…Differences in conformation are particularly marked before 60 years, with females presenting a more projected symphysis. Our results are in agreement with former studies, in which this region appears to be one of the most dimorphic in the mandible, with males presenting a higher, wider symphysis and less projected mental eminence than women [ 28 , 47 ]. As we saw previously that women present greater shape changes, our results seem to indicate that the female configuration shape draws nearer to the male configuration shape with aging, and that sexual dimorphism of conformation declines with age (Figs 7 and 8 ).…”

Section: Discussionsupporting

confidence: 94%

Sexual dimorphism of the mandibular conformational changes in aging human adults: A multislice computed tomographic study by geometric morphometrics

et al. 2021

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The aging process has an impact on mandibular bone morphology and can therefore affect shape sexual dimorphism. Understanding the effect of senescence on mandibular shape changes is particularly important to correctly estimate the sex of an individual and predict age-related conformational modifications. The purpose of this study was to assess age-related changes in mandibular shape and sexual dimorphism. The study sample comprised 160 Multi Slice Computed Tomography examinations of individuals aged 40 to 79 years. Geometric morphometric analysis of fourteen osteometric landmarks was used to examine sexual dimorphism and patterns of mandibular shape variation with age. Results showed that mandibular sexual dimorphism of shape remained significant with aging. Conformational changes occurred between 50 and 70 years and were different for male and female individuals. Females presented earlier and more marked age-related shape changes than males. These observations suggest that mandibular senescence is a sexually dimorphic process since its onset, rate, and the areas subjected to conformational changes differ from male to female individuals. Senescence-related changes present substantial variability, and further investigation is required to determine precisely the age that marks their onset.

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Section: Discussionsupporting

confidence: 94%

Sexual dimorphism of the mandibular conformational changes in aging human adults: A multislice computed tomographic study by geometric morphometrics

et al. 2021

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“…Evaluation of patient-specific anatomy for model development may require segmentation of medical images, which can be time-consuming and a significant barrier. Statistical shape modeling (SSM), which quantifies modes of geometric variation across a population through principal component analysis [97], has been employed in rapid reconstruction of 3D bone geometry without the need for segmentation [98,99]. SSM has the potential to be rapidly deployed for subject-specific modeling and surgical planning.…”

Section: Future Opportunities In Computational Modeling Of Reverse Total Shoulder Arthroplastymentioning

confidence: 99%

Complications of Reverse Total Shoulder Arthroplasty: A Computational Modelling Perspective

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Ernstbrunner

Robinson

et al. 2021

JCM

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Reverse total shoulder arthroplasty (RTSA) is an established treatment for elderly patients with irreparable rotator cuff tears, complex proximal humerus fractures, and revision arthroplasty; however, with the increasing indications for RTSA over the last decade and younger implant recipients, post-operative complications have become more frequent, which has driven advances in computational modeling and simulation of reverse shoulder biomechanics. The objective of this study was to provide a review of previously published studies that employed computational modeling to investigate complications associated with RTSA. Models and applications were reviewed and categorized into four possible complications that included scapular notching, component loosening, glenohumeral joint instability, and acromial and scapular spine fracture, all of which remain a common cause of significant functional impairment and revision surgery. The computational shoulder modeling studies reviewed were primarily used to investigate the effects of implant design, intraoperative component placement, and surgical technique on postoperative shoulder biomechanics after RTSA, with the findings ultimately used to elucidate and mitigate complications. The most significant challenge associated with the development of computational models is in the encapsulation of patient-specific anatomy and surgical planning. The findings of this review provide a basis for future direction in computational modeling of the reverse shoulder.

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“…We open our collection of papers with five studies investigating Population Anatomic Analysis and Model Reconstruction. The first paper (Vallabh et al 2019) presents an SSM of the human mandible and identifies sex-differentiating shape characteristics. They interrogated this model to identify key morphometric measurements to allow female and male shape reconstruction.…”

Section: Editorialmentioning

confidence: 99%