2023
DOI: 10.1093/cid/ciad384
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The Mortality of Infective endocarditis with and without Surgery in Elderly (MoISE) Study

Abstract: Background Infective endocarditis (IE) is increasingly affecting older patients, but data on their management are sparse and the benefits of surgery in this population are unclear. Methods We included patients with left-sided IE (LSIE) aged ≥ 80 years enrolled in a prospective endocarditis cohort managed in Aquitaine, France from 2013 to 2020. Geriatric data were collected retrospectively to identify factors associated with t… Show more

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Cited by 3 publications
(5 citation statements)
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“…The increasing prevalence of comorbidities in patients with IE makes it necessary to consider the role of treatment indications and the expected benefit of invasive interventions such as cardiac surgery, which is still controversial in many cases. 3 , 12 , 14 , 15 A high degree of comorbidity has led to a lower indication for surgery, especially in older patients. 3 As expected, comorbidities were higher in patients with intermediate and high frailty risk, and those with high frailty risk were older.…”
Section: Discussionmentioning
confidence: 99%
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“…The increasing prevalence of comorbidities in patients with IE makes it necessary to consider the role of treatment indications and the expected benefit of invasive interventions such as cardiac surgery, which is still controversial in many cases. 3 , 12 , 14 , 15 A high degree of comorbidity has led to a lower indication for surgery, especially in older patients. 3 As expected, comorbidities were higher in patients with intermediate and high frailty risk, and those with high frailty risk were older.…”
Section: Discussionmentioning
confidence: 99%
“…The proportion of women was similar in the three frailty states (around 40%), but was significantly lower in the group of patients undergoing valve surgery for IE, which has also been documented in previous studies. 15 , 17 , 18 , 19 …”
Section: Discussionmentioning
confidence: 99%
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“…However, it can also manifest in cases involving native valves [ 9 ]. Like other bacteria, the mortality rate linked to corynebacterial endocarditis ranges from 31% to 43% [ 9 , 10 ]. It is worth mentioning that endocarditis caused by C. striatum has the highest probability of survival compared to other types of Corynebacterium endocarditis [ 11 ].…”
Section: Discussionmentioning
confidence: 99%