The motor coordination activity of alcoholic extract of Withania coagulans fruits in Swiss albino mice by rota rod test

Gosavi, Devesh D; Kamdi, Amit S.; Kalambe, Suvarna M.; Bohra, Pankaj N.

doi:10.18231/j.ijpp.2020.015

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…The ripe fruits are utilized for Wound healing (Melguizo-Rodríguez et al, 2021) while dry fruits of W. coagulans are traditionally used as anti-diabetic (Ram et al, 2021) Anti-bacterial (Qasim et al, 2020) anti-microbial (Peerzade et al, 2002), hepatoprotective (Qureshi et al, 2019), hypolipidemic (Lateef and Qureshi, 2020), anti-oxidant (Keshari et al, 2018), anti-tumor (Ahmad et al, 2017), anti-depressant (Gosavi et al, 2020) immunosuppressive (Reddy et al, 2016;Mirakzehi et al, 2017), anti-inflammatory agent (Qureshi et al, 2019) diabetes treatment (Lateef and Qureshi, 2020). Seeds have anti-inflammatory, diuretic, and ophthalmia-curing properties, while flower buds have anthelmintic properties (Maurya and Jyendra, 2010;Mudassir et al, 2018;Saratha et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Potential and Phytochemical Study of Withania coagulans Dunal; Investigating the Herbal Medicine of Pakistan

Ali,

Rehman,

Aslam

et al. 2023

JIS

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| W. coagulans Dunal, belongs to Solanaceae family is a useful plant holding an important place in Ayurvedic medicines. Presence of biomedical compounds polyphenols, carotenoids, vitamins, and trace elements as secondary metabolites imparts antidiabetic, hepatoprotective, hypolipidemic, antidepressant, immunosuppressive, anti-microbial properties to the W. coagulans Dunal. Plant samples from Mianwalli, Kohat, and Sargodha city were gathered for antioxidant potential determination. Free radical scavenging activity and total antioxidant activity experiments were performed on the samples using the DPPH and Phosphomolybdenum methods. Results shows leaves extract from Mianwali has the highest total antioxidant capacity while stems collected form the Sargodha has highest free radicals scavenging ability with values of 47.60± 3.00 Vit C equiv mg/g DW and 50.00± 3.00 IC50 value.

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Section: Introductionmentioning

confidence: 99%

Antioxidant Potential and Phytochemical Study of Withania coagulans Dunal; Investigating the Herbal Medicine of Pakistan

Ali,

Rehman,

Aslam

et al. 2023

JIS

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Efficacy of Withania coagulans fruit extract as a coagulant for Mozzarella cheese at different coagulation temperatures from curd formation to pizza top

Nazish

Gulzar

Nadeem

et al. 2022

Food Processing Preservation

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Withania coagulans is a shrub that has milk‐clotting activity. Its coagulation efficiency at different concentrations and incubation temperatures was measured for Mozzarella cheese from curd formation to its application on the pizza top. Curd made at higher W. coagulans concentration (1%) has less coagulation time (1272.99 ± 96.68 s), viscosity (148.58 ± 9.25 Pa s), pH (5.89 ± 0.05), and yield (7.87 ± 0.53%) as compared to rest of samples. Increasing temperature (39°C) also decreased coagulation time (1599.19 ± 380.06 s), viscosity (146.56 ± 15.51 Pa s), pH (6.01 ± 0.17), and yield (8.87 ± 0.48%) of curd. W. coagulans at 0.2% concentration showed caseinolytic activity (78.83 ± 1.97%) very close to rennet (84.12 ± 2.3%). High W. coagulans and temperature conditions lead to the grainy texture that results in the loss of proteins, fats, and moisture from the cheese. Highest protein (21.89 ± 0.8%; 23.39 ± 2.15%), fat (17.64 ± 0.62%; 18.50 ± 0.32%), and moisture (43.55 ± 8.01%; 50.00 ± 6.13%) were observed in Mozzarella cheese at 0.2% W. coagulans concentration and 33°C temperature, respectively. This study showed that 0.2% extract of W. coagulans can be used to clot the milk for cheese production at 33°C. Novelty impact statement The interest in plant‐based coagulant consumption has been growing because of the rennet shortage and religious matters of some vegetarian people. A plant‐based coagulant from Withania coagulans has been reported for its milk‐clotting activity, but its behavior for Mozzarella cheese production from curd formation to its application on pizza topping needs detailed study for its use on an industrial scale. In this study, W. coagulans behavior was studied during curd formation. Its caseinolytic and proteolytic activities in comparison to rennet were studied. Mozzarella cheese physicochemical and functional characteristics on pizza topping were also described in this research.

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Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review

et al. 2021

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Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.

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The motor coordination activity of alcoholic extract of Withania coagulans fruits in Swiss albino mice by rota rod test

Cited by 3 publications

References 19 publications

Antioxidant Potential and Phytochemical Study of Withania coagulans Dunal; Investigating the Herbal Medicine of Pakistan

Antioxidant Potential and Phytochemical Study of Withania coagulans Dunal; Investigating the Herbal Medicine of Pakistan

Efficacy of Withania coagulans fruit extract as a coagulant for Mozzarella cheese at different coagulation temperatures from curd formation to pizza top

Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review

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