The Movement Disorders Society criteria for the diagnosis of Parkinson’s disease dementia: their usefulness and limitations in elderly patients

Kiesmann, Michèle; Chanson, Jean‐Baptiste; Godet, Julien; Vogel, Thomas; Schweiger, Laetitia; Chayer, Saïd; Kaltenbach, Georges

doi:10.1007/s00415-013-7018-8

Cited by 20 publications

(13 citation statements)

References 38 publications

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“…This study expands the results for validation efforts of the MDS Task Force diagnostic procedures for Level I and Level II criteria for PDD. Our study findings add to the efforts of other centers to validate these potentially useful criteria Given that the conventional approach to defining dementia in PD incorporates traditional neuropsychological testing, with its associated variability in test selection and often time‐consuming assessments, the MDS Task Force efforts have focused on ways to standardize testing that can be used across multiple centers and to identify time‐efficient methods to diagnose PDD.…”

Section: Discussionmentioning

confidence: 90%

Comparison of the Movement Disorder Society Parkinson's disease dementia criteria with neuropsychological testing

et al. 2014

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The objective of our study was to compare Movement Disorder Society Task Force criteria for diagnosis of Parkinson's disease dementia (PDD) with the gold standard of traditional neuropsychological testing. A short checklist (Level I) and a protocol of neuropsychological tests (Level II) have been proposed by a Movement Disorder Society Task Force but not fully validated in clinical practice. Ninety-one Parkinson's disease (PD) subjects were categorized as having dementia or no dementia based on a battery of neuropsychological test results and clinical judgment. The isolated components needed for Level I and Level II diagnoses were then culled from the neuropsychological evaluations and independently used to designate PDD. Compared with traditional neuropsychological testing, the sensitivity and specificity of Level I criteria for PDD was 66.7% and 98.8%, and for Level II criteria 100% and 92.7%, respectively. Using Level II criteria, 6 additional subjects were diagnosed with PDD that were classified as having no dementia when full neuropsychological data were used for the diagnosis. These 6 subjects had more education years and were less impaired on cognitive tests. The Movement Disorder Society's Level II criteria more frequently classify subjects with PDD than does traditional neuropsychological testing. Whereas Level II criteria may overclassify subjects as having PDD, they are very accurate in ruling out dementia. Movement Disorder Society's criteria are practical and timesaving, although full neuropsychological testing may still be needed.

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Section: Discussionmentioning

confidence: 90%

Comparison of the Movement Disorder Society Parkinson's disease dementia criteria with neuropsychological testing

et al. 2014

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“…This incidence was comparable to that found in some studies 35,36 but was inconsistent with that reported in some other studies. 32,[37][38][39] To our expectations, all the examined dementia scales (MMSE, MoCA, BD, RVR, DS, and FOME) demonstrated significant differences between patients with PDD and PDND. In ROC curve analysis, MMSE, MoCA, and BD showed better specificity and sensitivity when used alone.…”

Section: Discussionmentioning

confidence: 76%

Validation of Neuropsychological Tests to Screen for Dementia in Chinese Patients With Parkinson’s Disease

Qiao

Wang

et al. 2015

Am J Alzheimers Dis Other Demen

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To compare the accuracy of different neuropsychological tests and their combinations for deriving reliable cognitive indices for dementia diagnosis in Parkinson's disease (PD). One hundred forty consecutive patients with PD were recruited and administrated an extensive battery of neuropsychological tests. Discriminant analysis and receiver-operator characteristic curve were used to evaluate their correct classifications and validity. Patients with PD having dementia (PDD; 23.5%) performed significantly worse in all tests than patients without dementia. Age of onset, disease duration, Hoehn-Yahr grade, Unified Parkinson's Disease Rating Scale part III scores, and education were associated with dementia in patients with PD. Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment, and Block Design (BD) showed better specificity and sensitivity when used alone, and combined use of MMSE and BD further increased the validity. Our results indicated that the accuracy of MMSE was better in dementia diagnosis of Chinese patients with PD, and combined use of MMSE and BD could further increase the validity of dementia diagnosis.

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“…As a cross-sectional study, the limitations of this study include its sampling population, which consists of moderate to advanced PwP, restricting the applicability of the aforementioned findings to people with early stage or mild disease and precludes inferences about causality. Secondly, due to the retrospective nature of the study, the group with cognition disability was defined using the more generic cognition domain score on the FUNDES-Adult instead of tests such as the Mini Mental State exam or the Montreal Cognitive Assessment and definitions of the Movement Disorder Society criteria for PDD (39); cognition while those in this group may not strictly fulfill the diagnosis of "dementia" and may even include those with non-demented cognitive impairment, this method may have wider applicability in the primary care setting, providing an easier assessment of cognitive status for Physical Medicine and Rehabilitation physicians, physical therapists, or clinicians less familiar PDD diagnosis or when formal comprehensive neuropsychological testing cannot be conducted. Similarly, ambulation and walking status was evaluated by asking the patient to walk back and fro 3 m (domain 8.6 of FUNDES-Adult) instead of tests such as the Timed up and Go test.…”

Section: Discussionmentioning

confidence: 99%

Effect of Cognitive Disability and Ambulation Status on Functioning in Moderate-to-Advanced Parkinson Disease

Wang

Chan

et al. 2020

Front. Neurol.

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Background: As the disease progresses to moderate to advanced stages, people with Parkinson's disease (PwP) are likely to have various degrees of disability due to the motor and non-motor symptoms, such as ambulatory difficulty and cognitive impairment. The objective of this study was to investigate the impact of cognition and ambulation status on the functioning and disability of PwP using the World Health Orgnaization Disability Assessment Schedule 2.0 (WHODAS 2.0). Materials and Methods: A group of 10,581 PwP with Hoehn and Yahr Staging 3 and above were collected from a database of disability evaluation and functional assessment using the Taiwan Data Bank of Persons with Disability between July 2012 and October 2018. WHODAS 2.0 was administered and all PwP were grouped based on their ambulatory status, which was assessed by 3-m back and forth walk and cognitive ability, assessed by WHODAS 2.0 first domain with cutoff level at 58. Results: Non-ambulation and cognitive disability contributed independently to disability in all aspects of WHODAS 2.0 survey, including self-care, getting along with others, performing life activities and participation in society. Compared to ambulation status, cognitive disability had a greater negative impact on functioning in all aspects. Conclusion: Cognitive disability was associated with greater disability in moderate to advanced PwP than non-ambulatory status. The results of this study may indicate that cognition preservation is essential to ameliorate functional impairment and disability in moderate to advanced PwP.

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The Movement Disorders Society criteria for the diagnosis of Parkinson’s disease dementia: their usefulness and limitations in elderly patients

Cited by 20 publications

References 38 publications

Comparison of the Movement Disorder Society Parkinson's disease dementia criteria with neuropsychological testing

Comparison of the Movement Disorder Society Parkinson's disease dementia criteria with neuropsychological testing

Validation of Neuropsychological Tests to Screen for Dementia in Chinese Patients With Parkinson’s Disease

Effect of Cognitive Disability and Ambulation Status on Functioning in Moderate-to-Advanced Parkinson Disease

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