The MRI characteristics of non-mass enhancement lesions of the breast: associations with malignancy

Aydın, Hale

doi:10.1259/bjr.20180464

Cited by 41 publications

(59 citation statements)

References 30 publications

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“…Nevertheless, for the lesion with clustered ring enhancement, in addition to the risk of DCIS and invasive breast cancer, benign lesions such as complex sclerosis, papilloma and fibrocystic disease should also be taken into account [32]. The positive predictive value of clustered ring enhancement for malignancy varied greatly with the range of 41.9-100% due to the different patient populations between studies [30,[32][33][34]. The clustered enhanced ring used in the current study was referred to as multiple rings clustered together regardless of ring size, including the aforementioned clustered ring enhancement and larger rings clustered together which was not included in the 5th BI-RADS MRI lexicon.…”

Section: Discussionmentioning

confidence: 99%

“…Multivariate analyses showed that segmental distribution had the highest odds ratios of 4.739 and 5.1 for discriminating benign and malignant NME lesions [30, 31]. The positive predictive value for malignancy of segmental distribution ranged from 67 to 100% [34]. In the 5th edition lexicon, ductal distribution has been changed to the term “linear.” Linear distribution is divided into two patterns: single line or branching.…”

Section: Discussionmentioning

confidence: 99%

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Differentiation between Clinically Noninflammatory Granulomatous Lobular Mastitis and Noncalcified Ductal Carcinoma in situ Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Luo

Yu³

2020

Breast Care

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Introduction: Challenges in differentiation between clinically noninflammatory granulomatous lobular mastitis (GLM) and noncalcified ductal carcinoma in situ (DCIS) remain. Objective: To identify the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) characteristics contributing to their differential diagnosis. Methods: A total of 33 clinically noninflammatory GLM and 36 noncalcified DCIS were retrospectively analyzed in the study. Internal enhancement of a nonmass enhancement (NME) lesion was divided into clustered enhanced ring (absence/presence), and clustered enhanced ring (presence) was further classified as small and large ring based on the optimal cutoff value. The 5th Breast Imaging and Data System MRI descriptors were used for assessing the other DCE-MRI characteristics. Multivariate analysis including variables with significant differences in univariate analyses was conducted to identify the independent predictors. The discriminative abilities of different predictors and their combination were compared by area under the receiver-operating characteristic curves (AUCs). Results: An NME lesion was seen more commonly in clinically noninflammatory GLM than in noncalcified DCIS (p = 0.003). DCE-MRI characteristics with significant differences in univariate analyses included NME size, clustered enhanced ring (ab-sence/presence), ring size, initial increase and kinetic characteristics for the differentiation between these two entities presenting as NME lesion. Clustered enhanced ring (presence) was further classified as small (≤7 mm) or large ring (> 7 mm). Multivariate analysis revealed that internal enhancement and initial increase were identified as significant independent predictors, and the AUC of their combination achieved the highest value of 0.867 (95% CI, 0.748-0.943). Conclusions: An NME lesion with a large ring is more highly suggestive of clinically noninflammatory GLM.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Differentiation between Clinically Noninflammatory Granulomatous Lobular Mastitis and Noncalcified Ductal Carcinoma in situ Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Luo

Yu³

2020

Breast Care

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“…Aydin reviewed 129 NME lesions retrospectively aiming to differentiate between the benign versus malignant lesions [ 6 ]. He found that the segmental and diffuse distribution as well as clustered-ring internal enhancement was linked to malignancy; on the other hand, the linear distribution as well as homogeneous enhancement types were associated with benignity.…”

Section: Reviewmentioning

confidence: 99%

“…Some of these areas are identified as malignant, including IDC, ductal carcinoma in situ (DCIS) and tubular carcinoma. Others are diagnosed as benign masses, such as sclerosing adenosis, atypical ductal hyperplasia, fibroadenoma and mastitis [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging Features in Different Types of Invasive Breast Cancer: A Systematic Review of the Literature

Alaref¹,

Hassan²,

Kandel³

et al. 2021

Cureus

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Breast cancer is the most common malignancy affecting women worldwide, and early diagnosis of breast cancer is the key to its successful and effective treatment. Traditional imaging techniques such as mammography and ultrasound are used to detect and configure breast abnormalities; unfortunately, these modalities have low sensitivity and specificity, particularly in young patients with dense breast tissue, breast implants, or post-surgical scar/architecture distortions. Therefore, breast magnetic resonance imaging (MRI) has been superior in the characterization and detection of breast cancer, especially that with invasive features. This review article explores the importance of breast MRI in the early detection of invasive breast cancer versus traditional tools, including mammography and ultrasound, while also analyzing the use of MRI as a screening tool for high-risk women. We will also discuss the different MRI features for invasive ductal carcinoma and lobular carcinoma and the role of breast MRI in the detection of ductal carcinoma in situ with a focus on the utilization of new techniques, including MR spectroscopy and diffusion-weighted imaging.

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“…4).Das gruppierte und ringförmig gruppierte Muster des inneren Enhancements ist laut Studienergebnissen als suspekt zu werten (▶ Abb. 5)[9,10].…”

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MRT der Mamma: Befundung nach BI-RADS

Preibsch¹

2020

Radiologie up2date

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ZusammenfassungDie MRT der Mamma wird sowohl bei gesichertem Karzinom als auch im Rahmen der intensivierten Früherkennung immer häufiger eingesetzt. Basis dafür ist der in vielen Studien dargestellte Benefit in der prätherapeutischen Situation und als Screening-Methode im Hochrisikokollektiv. Die Aufgabe des Radiologen besteht darin, eine hohe Befundqualität zu gewährleisten. Die Kategorisierung nach BI-RADS ermöglicht dabei eine standardisierte Abschätzung der Malignitätswahrscheinlichkeit von Befunden.

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The MRI characteristics of non-mass enhancement lesions of the breast: associations with malignancy

Cited by 41 publications

References 30 publications

Differentiation between Clinically Noninflammatory Granulomatous Lobular Mastitis and Noncalcified Ductal Carcinoma in situ Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Differentiation between Clinically Noninflammatory Granulomatous Lobular Mastitis and Noncalcified Ductal Carcinoma in situ Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Magnetic Resonance Imaging Features in Different Types of Invasive Breast Cancer: A Systematic Review of the Literature

MRT der Mamma: Befundung nach BI-RADS

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