1985
DOI: 10.1016/s0046-8177(85)80152-0
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The mucosal changes and pathogenesis of pneumatosis cystoides intestinalis

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Cited by 128 publications
(56 citation statements)
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“…The first component is the mechanical aspect of gas traversing the mural portion Case Reports in Medicine 3 of the bowel. This can be precipitated by microbreaks in the mucosa, such as those caused by inflammation or necrosis; it can also be the result of direct gas diffusion across an intact mucosal membrane, as can occur in instances of increased transabdominal pressure [6,7]. The second aspect is the origin of the gas; while some amount of intramural gas is normally present in the human bowel, bacterial overgrowth and invasion of the bowel wall can result in excess gas production favoring the formation of PI [8].…”
Section: Discussionmentioning
confidence: 99%
“…The first component is the mechanical aspect of gas traversing the mural portion Case Reports in Medicine 3 of the bowel. This can be precipitated by microbreaks in the mucosa, such as those caused by inflammation or necrosis; it can also be the result of direct gas diffusion across an intact mucosal membrane, as can occur in instances of increased transabdominal pressure [6,7]. The second aspect is the origin of the gas; while some amount of intramural gas is normally present in the human bowel, bacterial overgrowth and invasion of the bowel wall can result in excess gas production favoring the formation of PI [8].…”
Section: Discussionmentioning
confidence: 99%
“…De acordo com a teoria mecânica, o gás disseca a parede intestinal através de disrupções da mucosa ou através da serosa a partir dos vasos mesentéricos. 4 A teoria bacteriana advoga que as bactérias formadoras de gás terão acesso à submucosa através de pontos de rotura da mucosa.…”
Section: Discussionunclassified
“…The first mechanical theory is that PCI occurs when intestinal gas is directly absorbed into the submucosa through damaged mucosa or when the gas in mesenteric blood vessels is absorbed into the subserosa [11,12]. This theory has been proposed to explain the occurrence of PCI in patients with ischemic bowel diseases or inflammatory and necrotic ones where the intestinal mucosa is damaged [13].…”
Section: Discussionmentioning
confidence: 99%