The Multifaceted Roles of Fungal Cutinases during Infection

Arya, Gulab Chand; Cohen, Hagai

doi:10.3390/jof8020199

Cited by 26 publications

(18 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These enzymes have been extensively studied due to their involvement both in natural and industrial processes. For example, in nature and industry they are essential in lignocellulose biodegradation [50], fungal pathogenesis [51] and the hydrolysis of triacylglycerol to fatty acids [52]. These enzymes also have applications in the food and textile industries [53][54][55], and in bioremediation processes [56,57].…”

Section: Fungal Enzymes Involved In Plastic Biodegradationmentioning

confidence: 99%

Fungal Enzymes Involved in Plastics Biodegradation

et al. 2022

View full text Add to dashboard Cite

Plastic pollution is a growing environmental problem, in part due to the extremely stable and durable nature of this polymer. As recycling does not provide a complete solution, research has been focusing on alternative ways of degrading plastic. Fungi provide a wide array of enzymes specialized in the degradation of recalcitrant substances and are very promising candidates in the field of plastic degradation. This review examines the present literature for different fungal enzymes involved in plastic degradation, describing their characteristics, efficacy and biotechnological applications. Fungal laccases and peroxidases, generally used by fungi to degrade lignin, show good results in degrading polyethylene (PE) and polyvinyl chloride (PVC), while esterases such as cutinases and lipases were successfully used to degrade polyethylene terephthalate (PET) and polyurethane (PUR). Good results were also obtained on PUR by fungal proteases and ureases. All these enzymes were isolated from many different fungi, from both Basidiomycetes and Ascomycetes, and have shown remarkable efficiency in plastic biodegradation under laboratory conditions. Therefore, future research should focus on the interactions between the genes, proteins, metabolites and environmental conditions involved in the processes. Further steps such as the improvement in catalytic efficiency and genetic engineering could lead these enzymes to become biotechnological applications in the field of plastic degradation.

show abstract

Section: Fungal Enzymes Involved In Plastic Biodegradationmentioning

confidence: 99%

Fungal Enzymes Involved in Plastics Biodegradation

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Cutinase is an enzyme that helps the fungus to penetrate the plant's cuticle, and it is also important for the survival of C. siamense in the environment in the absence of a host plant. 20 Based on our findings, we believe that cutinase is a potential target for the development of new fungicides. Given these findings, we expanded our investigation to a translational level by targeting the protein cutinase with the help of an in silico molecular docking study.…”

Section: ■ Introductionmentioning

confidence: 65%

In Vitro Insight on Antifungal-Specific Potentiality of Ni(II) Complex against Colletotrichum siamense and Fusarium equisetum Phytopathogens

Maity,

Sarkar

et al. 2023

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

In an initiation to investigate a prospective bioactive compound, a mononuclear Ni(II) complex with N, N, and O donor Schiff base ligand was synthesized and characterized in the present study through FTIR, ESI-mass, and X-ray crystallographic diffraction studies. A slightly distorted octahedral geometry has been obtained for the Ni(II) complex from X-ray crystallographic diffraction studies. In vitro comprehensive biological studies show the antifungal specific efficiency of the complex against Colletotrichum siamense (AP1) and Fusarium equisetum (F.E.) pathogens, which are responsible for anthracnose and wilt disease, respectively, but no inhibitory effect on both Gram-positive and Gram-negative bacteria. The minimum inhibitory concentration (MIC) for these pathogens was observed to be 0.25 and 0.5 mM, respectively. The experiment also reveals that significant damage of mycelia and enlarged, misshaped damaged spores are noticed in comparison to hexaconazole, used as a positive control under a light microscope post 48 h treatment of AP1 and F.E. with the MIC of the complex. The binding interaction studies of the complex with DNA and BSA performed through a variety of spectroscopic techniques demonstrate a strong binding behavior of the complex for both the binding systems. The observed negative ΔH° and ΔS° values for DNA reveal the existence of hydrogen-bonding/van der Waals interactions for DNA which was also exemplified from the molecular docking and self-assembly studies of the complex. The positive ΔH° and ΔS° values for BSA demonstrate the hydrophobic interactions of the complex with BSA. However, cytotoxicity studies against the MDA-MB-231 breast cancer cell line did not demonstrate any significant potentiality of the complex as an anticancer agent. All the bio-experimental studies provide clear evidence that the synthesized Ni(II) complex exhibits potential antifungal activity and could be used as a therapeutic fungicide agent in comparison to hexaconazole in agricultural practices.

show abstract

“…For example, C. funiculosum [ 38 ] and N. poaceicola [ 43 , 47 ] are saprobes as well as a plant pathogen [ 39 ], and N. rosigena is a saprobe [ 37 ]. Hydrolases and oxidoreductases of saprobic and pathogenic fungi are crucial for the degradation of lignocellulose [ 48 ] or pathogenesis [ 49 ]. Fungi containing various enzymes can biodegrade plastic substances [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Five Previously Unrecorded Fungal Species Isolated from Marine Plastic Wastes in South Korea

Kim

Lee

et al. 2022

Mycobiology

View full text Add to dashboard Cite

Plastic wastes have a negative impact on marine environments; however, they can be used as carbon sources and habitats by certain microbes. Microbes in the marine plastisphere can migrate worldwide through the ocean and cause serious environmental problems when they encounter suitable environments. Therefore, efforts to investigate the microbes inhabiting the marine plastisphere are increasing. In the present study, fungal strains were isolated from plastic wastes buried in Korean sea sands and mudflats and identified using molecular and morphological analyses. Five species were identified that were previously unrecorded from South Korea: Cladosporium funiculosum , Neosetophoma poaceicola , Neosetophoma rosigena , Parasarocladium gamsii , and Trichoderma fomiticola . Their molecular phylogenies and morphological characteristics are described in this study.

show abstract

The Multifaceted Roles of Fungal Cutinases during Infection

Cited by 26 publications

References 87 publications

Fungal Enzymes Involved in Plastics Biodegradation

Fungal Enzymes Involved in Plastics Biodegradation

In Vitro Insight on Antifungal-Specific Potentiality of Ni(II) Complex against Colletotrichum siamense and Fusarium equisetum Phytopathogens

Five Previously Unrecorded Fungal Species Isolated from Marine Plastic Wastes in South Korea

Contact Info

Product

Resources

About