The Nail Fold in Pemphigus Vulgaris

Nail Involvement in Pemphigus Vulgaris

“…Usually, fingernails were more often involved than tocnails and the temporal relationship of the nail involvement in PV is variable: it may be noted as part of the initial presentation, concomitant with disease relapse, or as a sign heralding exacerbation (2)(3)(4)(5)(6). In our series, nail involvement appeared after the first cutaneous or mucosal manifestation of pemphigus.…”

“…Beau's lines, pterygium. cross ridging, pitting, subunguai haemorrhage, and nail plate discoloration (2)(3)(4)(5)(6)(7)(8). There is only one paper describing nail involvement during pemphigus foHaceus (PF) (6).…”

Treatment of inflammatory nail disorders

“…A recent prospective study involving 79 patients with PV showed nail changes in 34.2% of the patients (72). Subungual bullae are often hemorrhagic and can cause nail bed detachment leading to onycholysis, subungual hemorrhages, and subungual hyperkeratosis (77,78). Severe nail changes are often associated with extensive and severe skin involvement.…”

Recurrent Paronychia as a Presenting Manifestation of Pemphigus Vulgaris: A Case Report

“…Nail disease can be a part of the initial presentation along with mucosal and cutaneous lesions, can precede a flare of the pre-existing disease, or can be the only sign of the disease [5,6,7,8,9,10,11,12,13]. It manifests as chronic paronychia, onychomadesis, Beau's lines, trachyonychia, onycholysis, subungual hemorrhage, nail plate discoloration, pitting, onychoschizia, and nail dystrophy [6,7,8,9,10,11,12,13,14,15,16,17,18,19].…”

“…It manifests as chronic paronychia, onychomadesis, Beau's lines, trachyonychia, onycholysis, subungual hemorrhage, nail plate discoloration, pitting, onychoschizia, and nail dystrophy [6,7,8,9,10,11,12,13,14,15,16,17,18,19]. Pseudopyogenic granuloma of the proximal or lateral nail fold can also be seen, and it has been reported to be the first symptom of a relapse of the disease [20].…”