Nano Research Young Innovators (NR45) Awards aims to recognize young researchers under the age of 45 for their distinguished accomplishments and/or their great potential to make substantial contributions in various fields of nanoscience and nanotechnology. Since the inaugural NR45 Awards launched in 2018, over a hundred innovators in nanobiotechnology, nanoenergy, and two-dimensional materials have been selected by the journal's editorial board [1-3]. The 2022 NR45 Awards highlight the research topic of nanocatalysis. Thirty outstanding young innovators were selected for their extraordinary contributions to the development of well-designed metals, metal oxides, single-atoms, and carbon-based nanocatalysts for important catalytic reactions related to energy applications. Congratulations to all the 30 awardees in 2022! The awardees contribute 15 research articles and 15 review articles to this special issue. Among the research articles on the light absorption behaviors for heterogeneous photosynthesis, Yi-Jun Xu from Fuzhou University reports a spherical SiO 2 support to manipulate the near-field scattering-promoted optical absorption of AuPd nanoalloys for enhanced Suzuki crosscoupling reactions [4]. Fuxiang Zhang from Dalian Institute of Chemical Physics, Chinese Academy of Sciences, presents a type of Sr 5 Nb 4 O 15-x N x layered perovskite oxynitride to extend the light absorption edge to 640 nm, showing an enhanced visible-light photocatalytic water oxidation activity [5]. In terms of applying the photothermal effect of nanocatalysts to utilize the full solar spectrum, Ghim Wei Ho from National University of Singapore summarizes the recent progress in photothermal catalysis for the solar-to-fuel generation [6]. Metal-support interactions in single-atom catalysis have attracted research interests in recent years. The special issue collects articles on the syntheses of advanced single-atom catalysts with well-designed metal-support interactions for various heterogeneous redox reactions. Wenyu Huang from Iowa State University demonstrates the cobalt-based single-atom catalysts by anchoring four-coordinated cobalt single sites on a nitrogenassembly mesoporous carbon support, showing excellent antipoisoning property for selective hydrogenation of nitroarenes [7]. Gang Liu from Institute of Metal Research, Chinese Academy of Sciences, reveals that the Ni(OH) 2 nanosheets modified with