2003
DOI: 10.1289/ehp.111-1241458
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The National Children's Study of environmental effects on child health and development.

Abstract: Increasing recognition that children may be more susceptible than adults to environmental exposures and that they experience potentially life-long consequences of such exposures has led to widespread support for a large new cohort study in the United States. In this article, we propose a framework for a new cohort study of children, with follow-up beginning before birth and continuing to age 21 years. We also describe the administrative structure that has been built to develop the proposal further. The structu… Show more

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Cited by 68 publications
(35 citation statements)
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“…It appears intriguing, however, that the rising incidence of childhood obesity and NAFLD has to some extent paralleled the diffusion of MSG addition to different classes of food. Although we cannot currently extend our observation to oral MSG administration in newborn mice, we submit that our observations should account for a rigorous re-evaluation of MSG safety, with particular regard to infant exposure, based on the growing evidence of developmental determinants in children [33].…”
Section: Discussionmentioning
confidence: 95%
“…It appears intriguing, however, that the rising incidence of childhood obesity and NAFLD has to some extent paralleled the diffusion of MSG addition to different classes of food. Although we cannot currently extend our observation to oral MSG administration in newborn mice, we submit that our observations should account for a rigorous re-evaluation of MSG safety, with particular regard to infant exposure, based on the growing evidence of developmental determinants in children [33].…”
Section: Discussionmentioning
confidence: 95%
“…Compared to other planned or recently started prospective birth-cohort studies, the size of the Generation R Study cohort is not larger but the measurements are more detailed [12][13][14][15][16]. The cohort is large enough to detect small effects of early environmental and genetic determinants on a variety of outcomes (Table 9 and 10).…”
Section: Strengthsmentioning
confidence: 99%
“…The National Children's Study is being planned with the goal of following 100 000 children from birth to age 21 years. 1 In that study parents will be asked periodically about the health of their children. Estimates of injury occurrence may be biased if recall is not accurate.…”
mentioning
confidence: 99%