The National Institute for Occupational Safety and Health Indoor Environmental Evaluation Experience. Part Three: Associations between Environmental Factors and Self-Reported Health Conditions

Sieber, William K.; Stayner, Leslie T.; Malkin, R.A.; Petersen, Martin R.; Mendell, Mark J.; Wallingford, Kenneth M.; Crandall, Michael S.; Wilcox, T.G.; Reed, Laurence D.

doi:10.1080/1047322x.1996.10389435

Cited by 52 publications

(42 citation statements)

References 11 publications

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“…In parallel, excess chest symptoms such as wheezing, chest tightness, and coughing (9) suggest that symptoms consistent with asthma are not infrequent, associated with moisture. Well-documented cases of disease appear to be accompanied by less clearly defined excess rates of upper airways symptoms, without clearly defined mechanisms (42,44).…”

Section: Symptoms Without Explained Physiology But With Objective Marmentioning

confidence: 99%

“…In the course of searching for moisture and humidifier fever (6) in buildings, Finnegan et al (7) found that symptoms were associated with humidification and ventilation. Subsequently, cross-sectional studies have supported an association of higher rates of symptoms with endotoxin exposure (8) and with the presence of unwanted moisture in ventilation systems (9).…”

Section: Is There a Basis For Feeling Sick In The Built Environment? mentioning

confidence: 99%

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Indoor environmental exposures and symptoms.

Hodgson

2002

Environ Health Perspect

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The label "sick building syndrome" is often used to imply the absence of a physiologic basis for symptoms in the built environment. Although building-related illness is widely recognized but considered rare, several well-studied mechanisms may be responsible for many symptoms in buildings. These mechanisms do not explain why some individuals perceive disability. Until researchers distinguish physiologic mechanisms from other aspects of disease and study them systematically, poorly defined symptoms will remain poorly understood. The disability associated with such symptoms and syndromes, not the physiology, is the primary interest and generates controversy.

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Section: Symptoms Without Explained Physiology But With Objective Marmentioning

confidence: 99%

Section: Is There a Basis For Feeling Sick In The Built Environment? mentioning

confidence: 99%

Indoor environmental exposures and symptoms.

Hodgson

2002

Environ Health Perspect

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“…35 In general, however, it has been concluded that the cause of symptoms in office workers is multifactorial, resulting from a complex combination of building-related factors, work organizational factors, and individual factors. Despite the difficulty in relating all the symptoms reported by the CSAs to specific work exposures, we did observe certain conditions at the airport that should be improved including potential for CO exposures, ETS, transient odors, temperature fluctuations, and communication deficiencies between management and employees.…”

Section: Discussionmentioning

confidence: 99%

HETA 97-0115-2718, Northwest Airlines, Wayne County Airport.

Roegner¹,

Baron²

1998

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“…Researchers have often treated the multiple symptoms reported in buildings as a single syndrome [e.g., Burge et al, 1987], although some researchers have considered sub-syndromes such as central nervous systems and mucus membrane irritation symptoms [Jaakkola and Miettinen, 1995;. Few reports have considered lower respiratory symptoms, which have been the least commonly reported symptoms studied in indoor environments Ruotsalainen et al, 1995;Sieber et al, 1996].…”

Section: Introductionmentioning

confidence: 99%

“…Recent studies have reported the association of risk factors in non-industrial indoor environments with increased work-related lower respiratory symptoms Ruotsalainen et al, 1995;Sieber et al, 1996]. For this analysis, we hypothesized that microbiologic contamination of indoor spaces or ventilation systems in office buildings may cause or exacerbate unrecognized building-related respiratory disease that presents as work-related lower respiratory symptoms.…”

Section: Introductionmentioning

confidence: 99%

Environmental risk factors and work‐related lower respiratory symptoms in 80 office buildings: An exploratory analysis of NIOSH data

Mendell

Naco

Wilcox

et al. 2003

American J Industrial Med

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Background: We evaluated relationships between lower respiratory symptoms and risk factors for microbiological contamination in office buildings.Methods: The National Institute for Occupational Safety and Health collected data from 80 office buildings during standardized indoor environmental health hazard evaluations. Present analyses included lower respiratory symptom-based outcome definitions and risk factors for potential microbiologic contamination. Multivariate logistic regression models for selected outcomes identified key risk factors.Results: Adjusted odds ratios (95% confidence intervals) for "at least three of four work-related lower respiratory symptoms" were, for debris in ventilation air intake, 2.0 (1.0-3.9), and for poor drainage in air-conditioning drip pans, 2.6 (1.3-5.2). Adjusted associations with risk factors were consistently stronger for outcomes requiring both multiple symptoms and improvement away from work, and somewhat stronger among diagnosed asthmatics.Conclusions: Moisture and debris in ventilation systems, possibly by supporting microbiologic growth, may increase adverse respiratory effects, particularly among asthmatics. Data from more representative buildings are needed to confirm these findings.

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The National Institute for Occupational Safety and Health Indoor Environmental Evaluation Experience. Part Three: Associations between Environmental Factors and Self-Reported Health Conditions

Cited by 52 publications

References 11 publications

Indoor environmental exposures and symptoms.

Indoor environmental exposures and symptoms.

HETA 97-0115-2718, Northwest Airlines, Wayne County Airport.

Environmental risk factors and work‐related lower respiratory symptoms in 80 office buildings: An exploratory analysis of NIOSH data

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