The national surveillance study of grass carp reovirus in China reveals the spatial-temporal characteristics and potential risks

Yang, Feng; Shi, Chao; Ouyang, Ping; Huang, Xiaoli; Chen, Defang; Qing, Wang; Yin, Jun; Zhang, Defeng; Geng, Yi

doi:10.1016/j.aquaculture.2021.737449

Cited by 8 publications

(3 citation statements)

References 15 publications

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“…It is important to note that many (bacterial) pathogens (and their respective strains/isolates) can be present in fish without clinical symptoms, as well as in surface water sources and wild aquatic animal populations (as hosts or carriers, also including invertebrates, birds etc.). From the autogenous vaccine development and use perspective, this situation can require that epidemiological links between current and potential disease outbreak sites are subjected to thorough analysis, possibly with the assistance of geographical information system-based models (Feng et al, 2022).…”

Section: Selection Of Pathogen Candidates For Autogenous Vaccine Deve...mentioning

confidence: 99%

Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics?

Palić

Aksentijević

2022

Vet glas

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New technological progress and increased demands for fish as a source of animal protein are driving significant growth of aquaculture production. Intensification of production increases the severity and frequency of infectious disease outbreaks, and so requires significant effort to prevent and control disease. Because of the global crisis of bacterial resistance to antibiotics, the use of antibiotics in aquaculture is increasingly subjected to strict control and regulatory measures, leading to potential misuse. The lack of availability of approved veterinary medical products for use in aquaculture, combined with the risk of drug resistance development and antibiotic residues in fish flesh or water, support the development of preventive actions, including vaccines. However, the diversity of species and aquaculture production methods, including epidemiological units and their links, results in economic challenges for commercial vaccine development and authorization. As a possible response to the increasing demand for less antibiotic use in fish farms, and to the expenses associated with novel veterinary product development, there is a need for increased use of safe and effective autogenous vaccines in aquaculture. Regulatory processes for autogenous vaccine production, approval and application should recognize the specificities of epidemiological units and their links in aquatic animal production facilities. The joint efforts of regulatory authorities, producers, and veterinary services to follow veterinary biosecurity principles, including risk analysis, surveillance, and selection/prioritization of pathogens, are essential to provide maximum safety and efficacy of autogenous vaccines as disease prevention and control tools within larger areas, such as compartments and zones, and allow for reductions in antibiotic use.

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Section: Selection Of Pathogen Candidates For Autogenous Vaccine Deve...mentioning

confidence: 99%

Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics?

Palić

Aksentijević

2022

Vet glas

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“…Grass carp ( Ctenopharyngodon idella ) is one of the most important aquaculture species worldwide, with over 6 million tons of annual production globally, the highest for any aquaculture species. Grass carp hemorrhagic disease (GCHD), caused by grass carp reovirus (GCRV), is one of the most damaging and contagious viral diseases, resulting in a greater than 80% mortality rate in yearly populations and huge economic losses to the grass carp aquaculture industry ( 1 , 2 ). GCRV, a double-stranded RNA virus of the genus Reoviridae , is the first aquatic virus isolated and characterized in China.…”

Section: Introductionmentioning

confidence: 99%

“…For decades, researchers and scientists have devoted much attention to studying the virus, from epidemiological studies to pathogen molecular biology and vaccine development ( 3 , 4 ). In general, the peak of GCHD incidence follows the higher-temperature months from June to September, when the optimum water temperature for GCHD outbreaks ranges from 27°C to 30°C ( 1 , 2 ). Thus, temperature is considered the key factor influencing GCRV transmission and pathogenesis.…”

Section: Introductionmentioning

confidence: 99%