2008
DOI: 10.1016/j.ophtha.2007.03.008
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The Natural History and Prognosis of Neovascular Age-Related Macular Degeneration

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Cited by 531 publications
(349 citation statements)
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References 85 publications
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“…1,3,5 The lower rate of 8.7% of patients developing nAMD in second eyes found in our study was probably due to the variable length of follow-up, which was inevitable in such a retrospective study. Nevertheless, the quantification of the proportion of patients with bilateral involvement in this study serves to highlight not only the burden on health care providers, with about 1 in 10 patients needing intensive treatment and visual rehabilitation for bilateral visual loss at any one time in a service of this nature but also the impact of visual loss on a sizeable proportion of elderly individuals.…”
Section: Discussionmentioning
confidence: 49%
See 1 more Smart Citation
“…1,3,5 The lower rate of 8.7% of patients developing nAMD in second eyes found in our study was probably due to the variable length of follow-up, which was inevitable in such a retrospective study. Nevertheless, the quantification of the proportion of patients with bilateral involvement in this study serves to highlight not only the burden on health care providers, with about 1 in 10 patients needing intensive treatment and visual rehabilitation for bilateral visual loss at any one time in a service of this nature but also the impact of visual loss on a sizeable proportion of elderly individuals.…”
Section: Discussionmentioning
confidence: 49%
“…In such patients who present with unilateral nAMD, the risk of second eye involvement in their good, fellow eyes has been estimated to be between 2 and 30% per year. 1,[3][4][5][6] This means that, in our clinical practice, a high proportion of patients present to us with unaffected, fellow eyes that are at a high risk of developing nAMD.…”
Section: Introductionmentioning
confidence: 99%
“…Noticeable declines in visual function do not occur until advanced forms of AMD, which may take years (Buschini et al 2015). Advanced AMD takes two primary forms defined by whether neovascularization occurs; geographic atrophy (GA) (Buschini et al 2015) presents with regional RPE cell death without blood vessel intrusion, while exudative (i.e., wet) AMD does (Wong et al 2008). Over three-quarters of legal blindness results from wet AMD (Buschini et al 2015), but GA accounts for the vast majority of advanced AMD cases ).…”
Section: Complement Inhibitors For Armdmentioning
confidence: 99%
“…In dry ARMD, deposits called drusen accumulate between the retina and the choroid, and slow degeneration of RPE and later photoreceptors leads to localized "geographic" atrophy and central vision loss. In wet ARMD, new, leaky blood vessels grow up from the choroid behind the retina, leading to acute vision loss (Wong et al, 2008). Retinitis pigmentosa is a collection of genetic diseases that generally start with night blindness and then continues on to tunnel vision, reflecting a pathology that affects rod photoreceptors in the peripheral retina earlier in the disease (Sahel et al).…”
Section: Pathologymentioning
confidence: 99%