The Natural History of Anencephaly

Obeidi, Nidaa; Russell, Nóirín; Higgins, John R.; O’Donoghue, Keelin

doi:10.1002/pd.2490

Cited by 71 publications

(55 citation statements)

References 28 publications

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“…The two most common types of NTDs are anencephaly, characterized by absence of much of the skull and brain, and spina bifida, a herniation of neural tissue through an incompletely formed spine (Botto et al, 1999). Anencephaly is a lethal condition and liveborn infants typically survive less than one day (Jaquier et al, 2006;Obeidi et al, 2010). The severity of spina bifida is more variable.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy termination following prenatal diagnosis of anencephaly or spina bifida: A systematic review of the literature

Johnson¹,

Honein²,

Flanders³

et al. 2012

Birth Defects Research

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Background-In regions where prenatal screening for anencephaly and spina bifida is widespread, many cases of these defects are prenatally diagnosed. The purpose of this study was to estimate the frequency of termination of pregnancy (TOP) following prenatal diagnosis of anencephaly or spina bifida and to investigate factors associated with TOP that might lead to selection bias in epidemiologic studies.

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Section: Introductionmentioning

confidence: 99%

Pregnancy termination following prenatal diagnosis of anencephaly or spina bifida: A systematic review of the literature

Johnson¹,

Honein²,

Flanders³

et al. 2012

Birth Defects Research

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show abstract

“…The most important reasons behind parents' happiness after the ultrasound scanning are finding out the baby's gender and receiving guarantee about their health (7). Given the public's increasing awareness about the benefits of ultrasound, demands have increased for performing ultrasound scanning by both doctors and patients (8). Moreover, recent developments in the prenatal diagnostic methods, especially prenatal ultrasound, have resulted in a better understanding of specific congenital anomalies; it has thus led to an improvement in the surgical as well as medical methods of treating birth defects (9).…”

Section: Introductionmentioning

confidence: 99%

The Study of Pregnant Women’s Attitude toward Using Ultrasound in Pregnancy and its Diagnostic Value based on the Demographic Features in Amir-al-Momenin Hospital of Zabol, 2015-2016

2017

Int. J. Adv. Res. Biol. Sci

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Ultrasound is widely used in pregnancy and it is considered as a part of the routine cares given in pregnancy. Ultrasound is also applied for screening during pregnancy. The present research aims at studying the pregnant women's attitudes toward using ultrasound in pregnancy and its diagnostic value based on the demographic variables in Amir-al-Momenin Hospital of Zabol from 2015 to 2016. The present study is a descriptive-analytical one conducted on pregnant women referring to Amir-al-Momenin Hospital of Zabol from 2015 to 2016. The questionnaire used in the present study was made by the Iranian gynecologists and radiologists; the questionnaire includes demographic features, the participant's pregnancy history, and the number of ultrasound performed during the recent pregnancy. The data collected were analyzed with respect to frequency, percentage, mean, and standard deviation through using SPSS 18. In the present study, from among the 300 patients studied, 148 patients (%49.3) were 20-30 years old, 96 patients (%32) experienced their third pregnancy, 112 patients (%37.3) had degrees lower than high school diploma, and 68 participants (%22.7) had college degrees. According to 223 participants (%74.3), ultrasound can show the fetus' physical problems. Moreover, 71 participants (23.7) believed that performing ultrasound in the second three months of pregnancy couldshow the fetus' chromosomal as well as genetic abnormalities. The findings of the present study indicated that most of t he patients maintain that ultrasound is necessary for their fetuses. They have also added that ultrasound can show the fetus' chromosomal-genetic abnormalities and its physical problems. It is recommended that training courses be provided to familiarize pregnant mothers with anomaly ultrasound.

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“…Isabela et al observed 64% of female anencephalic foetuses in their study (y) The female preponderance also reported by Jaquier et al 12 and James et al, 13 but study by Obeidi et al did not observed female preponderance. 14 Anencephaly associated anomalies ranges from 9.4 to 43%. 11,[16][17][18]20 In present study it was higher (78.12%) than previous studies but similar to study by C. Panduranga et al 73%.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of anencephaly associated anomalies

2020

IJCAP

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Introduction: Defective closure of rostral pore of neural tube leads to anencephaly. Folic acid deficiency is most common cause anencephaly. In most of the cases of Anencephaly is associated with other systemic anomalies. Objectives: Aim of present study was to find out the incidence of anencephaly associated systemic anomalies and their correlation with maternal age, sex of the foetus. Materials and Methods: 32 anencephaly foetuses obtained from the Department of obstetrics and gynaecology Navodaya Medical College. The period of study was from January 2013 to December 2016. Results: Out of 32 cases, 25(78.12%) cases showed presence of systemic anomalies associated with anencephaly, 53.12% of the cases were observed in primigravida. Most common associated anomaly was spinabifida 28.12% followed by gastrointestinal anomalies 6.25%. Conclusion: Incidence of anencephaly associated anomalies is not uncommon; hence gross systemic examination of the anencephalic abortus is required to find out incidence of anencephaly associated anomalies.

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The Natural History of Anencephaly

Abstract: This study provides useful information for health professionals caring for patients with a diagnosis of anencephaly. The majority of these infants die prior to delivery but short-term survival is possible.

Cited by 71 publications

References 28 publications

Pregnancy termination following prenatal diagnosis of anencephaly or spina bifida: A systematic review of the literature

Pregnancy termination following prenatal diagnosis of anencephaly or spina bifida: A systematic review of the literature

The Study of Pregnant Women’s Attitude toward Using Ultrasound in Pregnancy and its Diagnostic Value based on the Demographic Features in Amir-al-Momenin Hospital of Zabol, 2015-2016

Prevalence of anencephaly associated anomalies

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