The natural history of blood pressure in black populations in the West Indies, West Africa and the UK: a comparison with the USA

Cruickshank, J.K.

doi:10.1016/b978-0-7236-0916-2.50044-7

Cited by 3 publications

(2 citation statements)

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“…However, there remains some doubt whether this is and was so in unbiased genuinely representative population samples (now difficult to find) or after full adjustment for increased hypertension prevalence and other, including social, factors. That view, long considered here [ 32 , 33 ], was substantiated in the long-term follow-up of US studies [ 34 ], and recently in the long-term UK ‘SABRE’ study [ 35 ]. In the latter three-dimensional echo study, cardiac remodeling rather than hypertrophy was found to be the main issue.…”

Section: Discussionmentioning

confidence: 56%

Can arterial wave augmentation in young adults help account for variability of cardiovascular risk in different British ethnic groups?

Faconti

Silva

Molaodi

et al. 2016

Journal of Hypertension

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Objective:Traditional cardiovascular risk factors do not fully account for ethnic differences in cardiovascular disease. We tested if arterial function indices, particularly augmentation index (AIx), and their determinants from childhood could underlie such ethnic variability among young British adults in the ‘DASH’ longitudinal study.Methods:DASH, at http://dash.sphsu.mrc.ac.uk/, includes representative samples of six main British ethnic groups. Pulse wave velocity (PWV) and AIx were recorded using the Arteriograph device at ages 21–23 years in a subsample (n = 666); psychosocial, anthropometric, and blood pressure (BP) measures were collected then and in two previous surveys at ages 11–13 years and 14–16 years. For n = 334, physical activity was measured over 5 days (ActivPal).Results:Unadjusted values and regression models for PWVs were similar or lower in ethnic minority than in White UK young adults, whereas AIx was higher – Caribbean (14.9, 95% confidence interval 12.3–17.0%), West African (15.3, 12.9–17.7%), Indian (15.1, 13.0–17.2%), and Pakistani/Bangladeshi (15.7, 13.7–17.7%), compared with White UK (11.9, 10.2–13.6%). In multivariate models, adjusted for sex, central SBP, height, and heart rate, Indian and Pakistani/Bangladeshi young adults had higher AIx (β = 3.35, 4.20, respectively, P < 0.01) than White UK with a similar trend for West Africans and Caribbeans but not statistically significant. Unlike PWV, physical activity, psychosocial or deprivation measures were not associated with AIx, with borderline associations from brachial BP but no other childhood variables.Conclusion:Early adult AIx, but not arterial stiffness, may be a useful tool for testing components of excess cardiovascular risk in some ethnic minority groups.

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Section: Discussionmentioning

confidence: 56%

Can arterial wave augmentation in young adults help account for variability of cardiovascular risk in different British ethnic groups?

Faconti

Silva

Molaodi

et al. 2016

Journal of Hypertension

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“…Recent evidence from Jamaica shows an inverse relation between birthweight and blood pressure later in life 7 similar to that shown among adults in Britain 8 . Thus effective intervention against pre‐eclampsia and smallness for gestational age might reduce not only perinatal morbidity and mortality but also the high prevalence of later adult hypertension which is so common throughout the Caribbean and in adults of Caribbean origin elsewhere 9–11 .…”

Section: Introductionmentioning

confidence: 80%

Barbados Low Dose Aspirin Study in Pregnancy (BLASP): a randomised trial for the prevention of pre‐eclampsia and its complications

Rotchell

Cruickshank

Griffiths

et al. 1998

BJOG

171

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Objective To determine whether prophylactic, low dose controlled-release aspirin improves outcome for Design Randomised placebo-controlled trial.Setting The Queen Elizabeth Hospital, Barbados.Population All women attending antenatal clinics between 12 and 32 weeks of gestation were eligible, if without specific contraindications to aspirin and unlikely to deliver immediately.Methods Randomisation was computer-generated in the antenatal clinic; 1822 women were allocated to receive 75 mg controlled-release aspirin and 1825 matching placebo.Main outcome measures Proteinuric pre-eclampsia, other pregnancy-induced hypertension, pregnancy duration, birthweight, stillbirths and neonatal deaths, major neonatal events.Results All but three women from each group were followed up successfully. Forty-four percent were primigravid, and 8% had previous obstetric complications. There were no significant differences between the allocated treatment groups in the incidence of proteinuric pre-eclampsia ( ConclusionsThe results of this study in Barbados do not support the routine use of low dose aspirin for prevention of pre-eclampsia or its complications, confirming results of previous large trials in other pregnant women and their babies in Barbados.settings.

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Effects of sex, age, weight, and heredity on blood pressure in baboons

Kammerer

1995

American J Hum Biol

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Using data on a population of 498 pedigreed baboons, the effects of several covariates, including sex, age, weight, and subspecies, on arterial blood pressures were studied. Females had significantly higher systolic and diastolic arterial blood pressure than males. Both systolic and diastolic arterial blood pressures increased significantly with increasing weight, and for diastolic pressure, the increase was significantly greater in females than in males. Systolic arterial blood pressure significantly decreased with increasing age and the decrease was larger in males. There were significant differences in arterial blood pressures that corresponded with degree of subspecies admixture. © 1995 Wiley-Liss, Inc.

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The natural history of blood pressure in black populations in the West Indies, West Africa and the UK: a comparison with the USA

Cited by 3 publications

References 50 publications

Can arterial wave augmentation in young adults help account for variability of cardiovascular risk in different British ethnic groups?

Can arterial wave augmentation in young adults help account for variability of cardiovascular risk in different British ethnic groups?

Barbados Low Dose Aspirin Study in Pregnancy (BLASP): a randomised trial for the prevention of pre‐eclampsia and its complications

Effects of sex, age, weight, and heredity on blood pressure in baboons

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