The natural history of pediatric-onset discoid lupus erythematosus

Arkin, Lisa M.; Ansell, Leah; Rademaker, Alfred; Curran, Megan L.; Miller, Michael L.; Wagner, Annette; Kenner‐Bell, Brandi; Chamlin, Sarah L.; Mancini, Anthony J.; Klein-Gitelman, Marisa; Paller, Amy S.

doi:10.1016/j.jaad.2014.12.028

Cited by 45 publications

(29 citation statements)

References 33 publications

(45 reference statements)

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“…In 24-26% patients, childhood DLE may progress to SLE. [5,6] In 75% of the patients of pediatric SLE, the DLE lesions are present at the onset of systemic signs, but such children may fulfill the criteria for SLE much later; thus requiring a more prolonged follow up. Arthralgia and Raynaud's phenomenon are the most frequent systemic findings in pediatric DLE and inflammatory arthritis may herald progression to SLE.…”

Section: Discussionmentioning

confidence: 99%

Pediatric Discoid Lupus Erythematosus: successful treatment with antimalarials

Adlakha

Nagpal

Mahajan

et al. 2017

APALM

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Pediatric discoid lupus erythematous (DLE) is an uncommon entity that clinically resembles the adult onset DLE. However, pediatric DLE shows a higher incidence of positive family history and higher propensity towards progression to systemic lupus erythematous. Herein, we report a case of pediatric DLE who responded well to oral hydroxychloroquine. Keywords: Discoid Lupus Erythematous, Systemic Lupus Erythematous, Pediatric

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Section: Discussionmentioning

confidence: 99%

Pediatric Discoid Lupus Erythematosus: successful treatment with antimalarials

Adlakha

Nagpal

Mahajan

et al. 2017

APALM

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“…When systemic LE occurs in children, it is usually more aggressive. [5] Risk factors leading to systemic LE are not completely clear; however, a positive family history for autoimmune disorders, photosensitivity, and positive serologic findings are considered negative factors. [6]…”

Section: Discussionmentioning

confidence: 99%

A 14-year-old boy with an irregularly bordered, erythematous, alopecic patch of the scalp

2016

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“…One retrospective study of 40 children with DLE reported the greatest risk of progression to SLE was in the first year after DLE diagnosis. The majority of patients met SLE diagnostic criteria with mucocutaneous disease, cytopenia, and positive antibodies (75). Therefore, children with DLE should be very closely monitored for SLE development.…”

Section: Traumatic Hair Lossmentioning

confidence: 99%

A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents

Liu

Senna

2017

Front. Med.

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Hair loss or alopecia is a common and distressing clinical complaint in the primary care setting and can arise from heterogeneous etiologies. In the pediatric population, hair loss often presents with patterns that are different from that of their adult counterparts. Given the psychosocial complications that may arise from pediatric alopecia, prompt diagnosis and management is particularly important. Common causes of alopecia in children and adolescents include alopecia areata, tinea capitis, androgenetic alopecia, traction alopecia, trichotillomania, hair cycle disturbances, and congenital alopecia conditions. Diagnostic tools for hair loss in children include a detailed history, physical examination with a focused evaluation of the child's hair and scalp, fungal screens, hair pull and tug test, and if possible, light microscopy and/or trichoscopy. Management of alopecia requires a holistic approach including psychosocial support because treatments are only available for some hair loss conditions, and even the available treatments are not always effective. This review outlines the clinical presentations, presents a diagnostic algorithm, and discusses management of these various hair loss disorders.

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The natural history of pediatric-onset discoid lupus erythematosus

Cited by 45 publications

References 33 publications

Pediatric Discoid Lupus Erythematosus: successful treatment with antimalarials

Pediatric Discoid Lupus Erythematosus: successful treatment with antimalarials

A 14-year-old boy with an irregularly bordered, erythematous, alopecic patch of the scalp

A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents

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