2000
DOI: 10.1016/s0090-6980(00)00072-1
|View full text |Cite
|
Sign up to set email alerts
|

The nature and composition of 15-deoxy-Δ12,14PGJ2

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
28
0

Year Published

2001
2001
2010
2010

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 42 publications
(31 citation statements)
references
References 16 publications
2
28
0
Order By: Relevance
“…This was augmented by provision of arachidonate substrate, which itself upregulated expression of COX-2 (50), apparently the dominant source of 15d-PGJ 2 formation. However, the quantities of 15d-PGJ 2 formed are very small by comparison with conventional PGs (26,27).…”
Section: Discussionmentioning
confidence: 95%
See 2 more Smart Citations
“…This was augmented by provision of arachidonate substrate, which itself upregulated expression of COX-2 (50), apparently the dominant source of 15d-PGJ 2 formation. However, the quantities of 15d-PGJ 2 formed are very small by comparison with conventional PGs (26,27).…”
Section: Discussionmentioning
confidence: 95%
“…A commonly used immunoassay for the compound was withdrawn from the market (26). Dehydration and isomerization products of PGD 2 metabolism have been measured in humans (27).…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…6). As yet, there is no evidence for its formation by an enzymatic process (33). However, substantial levels of 15d-PGJ 2 have been detected by mass spectrometry in human urine (34) and in pleural exudate fluid after administration of carrageenin to rats (25).…”
Section: Discussionmentioning
confidence: 99%
“…15dPGJ 2 was purchased from Cayman Chemical (Ann Arbor, MI). 15dPGJ 2 is rapidly inter-converted to a mixture of at least five active isomers (29). Troglitazone was a generous gift from Parke Davis Warner Lambert (Plainsboro, NJ) and GW7647 (30), GW7845 (31), GW0742 (32), and GW9662 (33) were generous gifts from Dr. Timothy M. Willson and Dr. Peter J.…”
Section: Cells and Reagentsmentioning
confidence: 99%