Background. Anomie at work is a type of social anomie interrelated with professional activities that entail employees being exposed to repeated temptations. Under such conditions they come up with credible justifications that become fixed. Anomie manifests itself in organisations where there are values that have even been written down, but they are not held on to. One should seek the sources of anomie in the organisational culture, organisational structure, organisation of work, motivation and management methods, legal rules as well as in human behaviours and value systems, and in the mechanisms regulating social behaviours in an organisation. The phenomenon of anomie at work is part of the nature of any business, but every ethical act limits it. The objective of this paper is to analyse anomie at work, the conditioning and causes of this phenomenon, and methods of dealing with anomie at work.