The Nature of the Pressor and Depressor Factors Derived from the Kidney

Oxidation of Proteins by Tyrosinase and Peroxidase

“…The substrate hypertensinogen is converted to hypertensin by renin, and the hypertensin in turn must be assayed by its effect in elevating the blood pressure of dogs or rats. In the absence of added phenolic compounds renin is partially inactivated by tyrosinase (65,68). The inactivation process can be followed by measuring the oxygen consumption of the system (65).…”