The need to promote sleep health in public health agendas across the globe

Lim, Diane C; Najafi, Arezu; Afifi, Lamia; Bassetti, Claudio LA; Buysse, Daniel J; Han, Fang; Högl, Birgit; Melaku, Yohannes Adama; Morin, Charles M; Pack, Allan I; Poyares, Dalva; Somers, Virend K; Eastwood, Peter R; Zee, Phyllis C; Jackson, Chandra L

doi:10.1016/s2468-2667(23)00182-2

Cited by 79 publications

(25 citation statements)

References 79 publications

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“…Importantly, SWCDs and sleep loss increase the Swiss data confirm the high prevalence of such sleep complaints as insomnia (36% of 2432 subjects) and sleepiness (25% of 4901 subjects) [4,5]. Importantly, SWCDs and sleep loss increase the risk of medical (e.g., metabolic, cardiovascular), neurological (e.g., neurodegenerative), and psychiatric disorders and negatively modulate their course [1,6,7].…”

Section: Introductionmentioning

confidence: 73%

“…Sleep-wake circadian disorders (SWCDs) and sleep loss represent a major burden for our society in terms of health, financial, and societal consequences. Importantly, sleep-wake disorders have a massive impact on the quality of life of patients and those living around them [1]. Sleep loss affects over 25% and SWCDs over 30% of the population [2,3].…”

Section: Introductionmentioning

confidence: 99%

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The International Master of Advanced Studies (MAS) in Sleep Medicine of the Universities of Bern and Svizzera Italiana

Bassetti,

Sohm,

Adamantidis

et al. 2024

CTN

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Introduction: Sleep–wake circadian disorders (SWCDs) are very frequent and linked to major negative effects on the body, mental health, the brain, and on occupational and societal health. The prevention, diagnosis, and treatment of SWCDs and the promotion of sleep health require the sufficient education of general practitioners, specialists, and other health professionals. Unfortunately, education at pre- and postgraduate level is insufficient in most countries across the world. Aims and methods: This article describes the historical context, basic considerations, and methodological approach for the creation of the International Postgraduate Sleep Master by the University of Bern and Svizzera Italiana. Results: The postgraduate Master, which was launched in 2017, is a part-time, flexible course, taken over 2 ½ years, which targets health professionals, scientists, and technicians. After an initial introduction, which is the same for everybody (“common trunk”), the course can be individualized. The 12 modules of the Master include online lectures, schools, internships in a sleep center (in one of our 15 partner universities), case discussions and interactive sessions with students and internationally recognized experts from over 20 countries across the world, and culminates with a Master thesis. The program covers sleep–wake circadian biology; the management of SWCDs; disturbances of consciousness and sleep-related epilepsies; novel approaches in sleep medicine (e.g., clinical trials, telemedicine, data science, artificial intelligence); and topics of increasing relevance (e.g., neurodegenerative disorders, gender and diversity, sleep health, new technologies, artificial intelligence, professional and societal implications). Students are encouraged to also take “crash courses” in preparation for the national, European, and World sleep examinations. Conclusion: The Postgraduate University Sleep Master of the Universities of Bern and Svizzera Italiana offers a unique part-time, (mainly) virtual opportunity to acquire state-of the art knowledge, skills, and professional experiences to prepare for a clinical or scientific career in sleep medicine for physicians, scientists, and other health professionals.

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Section: Introductionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

The International Master of Advanced Studies (MAS) in Sleep Medicine of the Universities of Bern and Svizzera Italiana

Bassetti,

Sohm,

Adamantidis

et al. 2024

CTN

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“…The awareness and interest surrounding sleep as a crucial pillar of health is growing rapidly 85 . However, the role of sleep in general health is complex and multifaceted, and largely unknown.…”

Section: Discussionmentioning

confidence: 99%

A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures

Perrault,

Kebets,

Kuek

et al. 2024

Preprint

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Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological and socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep is rarely capitalized on in research. Here, we deployed a data-driven approach to identify sleep-biopsychosocial profiles that linked self-reported sleep patterns to inter-individual variability in health, cognition, and lifestyle factors in 770 healthy young adults. We uncovered five profiles, including two profiles reflecting general psychopathology associated with either reports of general poor sleep or an absence of sleep complaints (i.e., sleep resilience) respectively. The three other profiles were driven by sedative-hypnotics-use and social satisfaction, sleep duration and cognitive performance, and sleep disturbance linked to cognition and mental health. Furthermore, identified sleep-biopsychosocial profiles displayed unique patterns of brain network organization. In particular, somatomotor network connectivity alterations were involved in the relationships between sleep and biopsychosocial factors. These profiles can potentially untangle the interplay between individuals’ variability in sleep, health, cognition and lifestyle — equipping research and clinical settings to better support individual’s well-being.

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“…Sleep is an essential biological process, orchestrated by interrelated neurologic and physiologic regulatory processes, responding to individual, social, and environmental influences [1][2][3] . Positive sleep traits have been associated with lower rates of cardiometabolic and neuropsychiatric diseases, as well as higher productivity and well-being 4 . Moreover, general sleep health has come into recent focus as a consequential and modifiable health factor, with the combined presence of multiple healthy sleep factors frequently being a stronger predictor of positive health outcomes 5,6 .…”

Section: Introductionmentioning

confidence: 99%

Genome-wide association analysis of composite sleep health scores in 413,904 individuals

Goodman,

Faquih,

Paz

et al. 2024

Preprint

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Recent genome-wide association studies (GWASs) of several individual sleep traits have identified hundreds of genetic loci, suggesting diverse mechanisms. Moreover, sleep traits are moderately correlated, and together may provide a more complete picture of sleep health, while also illuminating distinct domains. Here we construct novel sleep health scores (SHSs) incorporating five core self-report measures: sleep duration, insomnia symptoms, chronotype, snoring, and daytime sleepiness, using additive (SHS-ADD) and five principal components-based (SHS-PCs) approaches. GWASs of these six SHSs identify 28 significant novel loci adjusting for multiple testing on six traits (p<8.3e-9), along with 341 previously reported loci (p<5e-08). The heritability of the first three SHS-PCs equals or exceeds that of SHS-ADD (SNP-h2=0.094), while revealing sleep-domain-specific genetic discoveries. Significant loci enrich in multiple brain tissues and in metabolic and neuronal pathways. Post GWAS analyses uncover novel genetic mechanisms underlying sleep health and reveal connections to behavioral, psychological, and cardiometabolic traits.

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The need to promote sleep health in public health agendas across the globe

Cited by 79 publications

References 79 publications

The International Master of Advanced Studies (MAS) in Sleep Medicine of the Universities of Bern and Svizzera Italiana

The International Master of Advanced Studies (MAS) in Sleep Medicine of the Universities of Bern and Svizzera Italiana

A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures

Genome-wide association analysis of composite sleep health scores in 413,904 individuals

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