1964
DOI: 10.1113/expphysiol.1964.sp001737
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The Nephropathy of Experimental Magnesium Deficiency: An Electron Microscopic Study

Abstract: Thirty rats were divided into three equal groups; the control group C and the two experimental groups were fed on diets identical in all respects other than the magnesium content. Group A were kept on a magnesium deficient diet for 13 days, and group B for 3 days. At the end of the experimental period, muscle, kidney and plasma were analyzed for their Mg and Ca contents and the kidneys were examined by the light and electron microscopes. No significant change was noted in the magnesium content of the kidneys o… Show more

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Cited by 11 publications
(3 citation statements)
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“…In the bend of the loop below the calculus, isolated bits of debris from the erosion of the epithelial wall of the preceding portion of the tubule lie within the still intact basement membrane of the first portion of the thin limb; similar shreds of material are scattered along the length of the tenuous ascending portion of the thin limb and are present throughout its gradual transition into the first portion of the broad ascending limb of Henle's loop, Figs. 14~ (5). This cellular debris stains deeply with iron hematoxylin but in other similar dissected specimens was negative to the alizarin stain.…”
Section: Structural Alterationsmentioning
confidence: 89%
See 1 more Smart Citation
“…In the bend of the loop below the calculus, isolated bits of debris from the erosion of the epithelial wall of the preceding portion of the tubule lie within the still intact basement membrane of the first portion of the thin limb; similar shreds of material are scattered along the length of the tenuous ascending portion of the thin limb and are present throughout its gradual transition into the first portion of the broad ascending limb of Henle's loop, Figs. 14~ (5). This cellular debris stains deeply with iron hematoxylin but in other similar dissected specimens was negative to the alizarin stain.…”
Section: Structural Alterationsmentioning
confidence: 89%
“…More recently electron microscopy has been applied to the examination of the lesion. In one study (5) early dilatation of the lumens of the proximal convolutions is described; the mitochondria of the cells of these tubules are described as normal.…”
mentioning
confidence: 99%
“…Ce syn drome est connu pour être associé à une élévation du seuil d'excrétion des bicarbonates, si bien que l'augmentation du nombre des cellules intercalaires peut correspondre là encore à des transferts accrus d'ions H CO 3. Des faits proches peuvent être trouvés dans les résultats de MacD onald [12]. En revanche, H ancox et Komender [10] signalent une relation entre l'abondance des cellules intercalaires et la concen tration des urines.…”
Section: Discussionunclassified