The encompassing scale and scope of International Political Economy (IPE) is rare in the social sciences. Our subject matter affects the way our field organizes and produces knowledge: we study complex overlapping systems where the challenges of adequate description and causal explanation are especially difficult, and as such IPE scholarship borrows from a vast range of social theory and methods. While holding enormous productive potential, this space for pluralism, as currently practiced, risks culminating in the fragmentation of knowledge: what I call 'alienated pluralism'. A different, 'engaged pluralism' as I propose would retain the diversity of IPE's many approaches and traditions, but would promise greater knowledge synthesis. I argue that stronger adherence to a scientific ethos can assist in building this 'engaged pluralism'.