The neural correlates of gait improvement by rhythmic sound stimulation in adults with Parkinson's disease – A functional magnetic resonance imaging study

Nishida, Daisuke; Mizuno, Katsuhiro; Yamada, Eiji; Hanakawa, Takashi; Liu, Meigen; Tsuji, Takao

doi:10.1016/j.parkreldis.2021.02.010

Cited by 9 publications

(8 citation statements)

References 35 publications

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“…Previous studies indicated that the overactivated parietal operculum was related to severer motor dysfunctions in PD (Herz et al, 2014;Nishida et al, 2021). In detail, a meta-analysis of 24 functional neuroimaging studies demonstrated that the parietal area is relatively overactivated during motor execution or imagery in PD patients (Herz et al, 2014), and another study revealed that the reduced activity of parietal operculum could alleviate the motor disfunctions in PD (Nishida et al, 2021). All of these indicated that after levodopa administration, the reduced activity of parietal operculum which was under cholinergic innervation was an important characteristic for the DA-responsive tremor in PD.…”

Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 97%

“…The parietal area is a core region where the anticholinergic medication functioned on (P. H. Lee et al, 2008), which suggests that the parietal operculum is under cholinergic control and is closely related to cholinergic modulation. The parietal operculum contains secondary somatosensory area and is densely connected to both somatosensory and motor areas, linking it to sensorimotor integration and motor control (Eickhoff et al, 2010;Jackson et al, 2011), which plays an important role in the motor performance for PD (Nishida et al, 2021;Sharman et al, 2013). Previous studies indicated that the overactivated parietal operculum was related to severer motor dysfunctions in PD (Herz et al, 2014;Nishida et al, 2021).…”

Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 99%

“…The parietal operculum contains secondary somatosensory area and is densely connected to both somatosensory and motor areas, linking it to sensorimotor integration and motor control (Eickhoff et al, 2010;Jackson et al, 2011), which plays an important role in the motor performance for PD (Nishida et al, 2021;Sharman et al, 2013). Previous studies indicated that the overactivated parietal operculum was related to severer motor dysfunctions in PD (Herz et al, 2014;Nishida et al, 2021). In detail, a meta-analysis of 24 functional neuroimaging studies demonstrated that the parietal area is relatively overactivated during motor execution or imagery in PD patients (Herz et al, 2014), and another study revealed that the reduced activity of parietal operculum could alleviate the motor disfunctions in PD (Nishida et al, 2021).…”

Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 99%

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Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson’s disease

Zhou

Guo

et al. 2022

Brain Imaging and Behavior

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Tremor in Parkinson’s disease (PD) has distinct responsiveness to dopamine, which is supposed not be exclusively related to dopamine deficiency but has a close relationship with cholinergic system. This phenomenon indicates that cholinergic system may be an important regulatory for distinct dopamine responsiveness of parkinsonian tremor. Through investigating the alterations of cholinergic and dopaminergic network during levodopa administration, we aimed at exploring the mechanisms of differed dopamine responsiveness of parkinsonian tremor. Fifty-two PD patients with tremor were enrolled. MRI scanning, UPDRS III and its sub-symptom scores were collected in OFF and ON status (dopaminergic challenge test). Then, patients were divided into two groups (dopamine-resistant tremor and dopamine-responsive tremor) according to the tremor change rate median score. Dopaminergic and cholinergic network were obtained. LASSO regression was conducted to identify functional connectivity with distinct reactivity during levodopa administration between groups. Afterwards, detailed group comparisons, interaction and correlation analyses were performed. The reactivity of cholinergic connectivity showed the highest possibility to distinguish two groups, especially connectivity of right basal forebrain 123 to right parietal operculum cortex (R.BF123-R.PO). After levodopa administration, connectivity of R.BF123-R.PO was decreased for dopamine-responsive tremor while which remained unchanged for dopamine-resistant tremor. The reactivity of R.BF123-R.PO was negatively correlated with tremor change rate. Reduced cholinergic connectivity to parietal operculum may be an underlying mechanism for the responsive tremor in PD and the distinct cholinergic reactivity of parietal operculum to levodopa may be a core pathophysiology for the differed DA responsiveness of tremor in PD.

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Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 97%

Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 99%

Section: Cholinergic Reactivity Of Parietal Operculum Is Distinct Among Pd Patients With Differed Da Responsiveness Of Tremormentioning

confidence: 99%

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Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson’s disease

Zhou

Guo

et al. 2022

Brain Imaging and Behavior

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“…fNIRS is utilized to concentrate on the brain areas of interest in eleven sicknesses, including stroke, MCI, traumatic brain injury, and harm recognition [ 7 ]. There are several modalities used to acquire brain signals for rehabilitation, such as magnetic field measurement using magnetoencephalography (MEG) [ 8 , 9 ], electroencephalography (EEG), radioactive tracer-based positron emission tomography (PET) [ 10 , 11 ], functional magnetic resonance imaging (fMRI) [ 12 , 13 ], gamma emission-based single-photon emission computed tomography (SPECT) [ 14 , 15 ], and fNIRS. fNIRS is widely used due to its advantages of mobility and ease of use compared to other neuroimaging modalities when researching the brain basis of cognitive inputs during gait [ 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

LASSO Homotopy-Based Sparse Representation Classification for fNIRS-BCI

Gulraiz

Naseer

Nazeer

et al. 2022

Sensors

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Brain-computer interface (BCI) systems based on functional near-infrared spectroscopy (fNIRS) have been used as a way of facilitating communication between the brain and peripheral devices. The BCI provides an option to improve the walking pattern of people with poor walking dysfunction, by applying a rehabilitation process. A state-of-the-art step-wise BCI system includes data acquisition, pre-processing, channel selection, feature extraction, and classification. In fNIRS-based BCI (fNIRS-BCI), channel selection plays a vital role in enhancing the classification accuracy of the BCI problem. In this study, the concentration of blood oxygenation (HbO) in a resting state and in a walking state was used to decode the walking activity and the resting state of the subject, using channel selection by Least Absolute Shrinkage and Selection Operator (LASSO) homotopy-based sparse representation classification. The fNIRS signals of nine subjects were collected from the left hemisphere of the primary motor cortex. The subjects performed the task of walking on a treadmill for 10 s, followed by a 20 s rest. Appropriate filters were applied to the collected signals to remove motion artifacts and physiological noises. LASSO homotopy-based sparse representation was used to select the most significant channels, and then classification was performed to identify walking and resting states. For comparison, the statistical spatial features of mean, peak, variance, and skewness, and their combination, were used for classification. The classification results after channel selection were then compared with the classification based on the extracted features. The classifiers used for both methods were linear discrimination analysis (LDA), support vector machine (SVM), and logistic regression (LR). The study found that LASSO homotopy-based sparse representation classification successfully discriminated between the walking and resting states, with a better average classification accuracy (p < 0.016) of 91.32%. This research provides a step forward in improving the classification accuracy of fNIRS-BCI systems. The proposed methodology may also be used for rehabilitation purposes, such as controlling wheelchairs and prostheses, as well as an active rehabilitation training technique for patients with motor dysfunction.

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“…Forte & De Vito., 2021). Studies show that treatment program based on RAS ameliorate the motor action in this population Koshimori & Thaut, 2018;Nishida, et al, 2021).…”

Section: Parkinsons's Disease: a Systematic Reviewmentioning

confidence: 99%

The complexity of an artwork affects the subjective perception of time and bimanual motor activity performed in the presence and absence of music of the patients with Parkinson\'s disease

Motta¹

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por toda dedicação, atenção e apoio durante toda a trajetória de desenvolvimento desta tese. Ao Dr. Vitor Tumas e sua equipe por todo o acolhimento, apoio e incentivo. Ao Conselho Nacional de Desenvolvimento Científico e Tecnológico -CNPq pelo apoio financeiro. À Coordenação de Aperfeiçoamento de Pessoal de Nível Superior -CAPES por financeiramente possibilitar que parte do meu doutorado fosse realizado no exterior. À Universidade de Tufts pela oportunidade de enriquecimento científico. À Dra. Linda Tickle-Degnen e sua equipe por me receberem de modo especial e por fazerem parte desta caminhada. E a todos que direta ou indiretamente contribuíram para que a jornada que levou até essa tese pudesse ser concluída. Palavras-chave: Percepção do tempo. Obra de Arte. Música. Atividade Motora. Doença de Parkinson.

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The neural correlates of gait improvement by rhythmic sound stimulation in adults with Parkinson's disease – A functional magnetic resonance imaging study

Cited by 9 publications

References 35 publications

Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson’s disease

Cholinergic relevant functional reactivity is associated with dopamine responsiveness of tremor in Parkinson’s disease

LASSO Homotopy-Based Sparse Representation Classification for fNIRS-BCI

The complexity of an artwork affects the subjective perception of time and bimanual motor activity performed in the presence and absence of music of the patients with Parkinson\'s disease

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